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TNFRSF13B Antibodies
AND TNFRSF13B ELISA kits, TNFRSF13B Proteins
Many biological assays use antibodies to detect TNFRSF13B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF13B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF13B antibodies...
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TNFRSF13B Infographic by Boster Bio
All TNFRSF13B Products
Product
Figures
Specificity
Applications
Price
Human TNFRSF13B/TACI ELISA Kit PicoKine®
3 Citations 6 Q&As
Human
ELISA
$499
Cat # EK0986
96 wells/kit, with removable strips.
Cat # EK0986
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1144
96 wells/kit, with removable strips.
Cat # EK1144
96 wells/kit, with removable strips.
TNFRSF13B Overview
Facts about Tumor necrosis factor receptor superfamily member 13B.
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B)
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, along with activation of NF-kappa-B and AP-1.
Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF13B |
| Uniprot: | O14836 |
| Entrez: | 23495 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD267 antigen; CD267; CVID; CVID2; FLJ39942; MGC133214; TACI; TACIMGC39952; TNFRSF13B; TNFRSF14B; Transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B
Molecular Weight
Mass (kDA):
31.816 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p11.2 |
| Sequence: | 17; NC_000017.11 (16939081..16972118, complement) |
Tissue Specificity
Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B- cells and activated T-cells, but not in resting T-cells.
Subcellular Localizations
Membrane; Single-pass type III membrane protein.
Diseases
- Immunologic Deficiency Syndromes
- Common Variable Immunodeficiency
- Autoimmune Reaction
- Autoimmune Diseases
- Autoimmunity
- Malignant Neoplasms
- Neoplasms
- Infective Disorder
- Immunoglobulin A Deficiency (disorder)
- Lupus Erythematosus, Systemic
- Lymphoma
- Multiple Myeloma
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- MYD88
- SGTA
- TNFSF13B
Pathways
- Cell Maturation
- Pathogenesis
- Cell Activation
- Secretion
- Cell Proliferation
- Cell Differentiation
- B Cell Activation
- Immunoglobulin Production
- Cell Development
- B Cell Proliferation
- Isotype Switching
- B Cell Homeostasis
- Cell Growth
PTMs
- Phosphorylation
Research Areas
- Apoptosis
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF13B
bosterbio.com/bosterbio-gene-info-cards/TNFRSF13B
References
PMID: 9311921 by von Buelow G.-U., et al. NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily.
PMID: 10956646 by Wu Y., et al. Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS.
3 Publications of Boster TNFRSF13B Antibodies & ELISA Kits
- PubMed ID: 10.3892/etm.2016.3157, Characteristics of CD4+CD25+Foxp3+ regulatory T cells in patients with multiple ...
- PubMed ID: 10.1007/s12288-018-1029-7, Prognostic Significance of Serum BAFF, APRIL, TACI and BCMA Levels in Chronic Ly...
- PubMed ID: 27168826, Characteristics of CD4+CD25+Foxp3+?regulatory T cells in patients with multiple ...
*More publications can be found for each product on its corresponding product page