Anti-T-cadherin ENTPD3 Antibody

Product Name

Anti-T-cadherin ENTPD3 Antibody

View all CD39L3/ENTPD3 Antibodies

SKU/Catalog Number

A10606

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-T-cadherin ENTPD3 Antibody (Catalog # A10606). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

T-cadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-T-cadherin ENTPD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A10606)

Host

Rabbit

Contents

T-cadherin Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin. The immunogen is located within amino acids 150 - 200 of T-cadherin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least two isoforms of T-cadherin are known to exist.

Reactive Species

A10606 is reactive to ENTPD3 in Human, Mouse

Applications

A10606 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

59105 MW

Background of CD39L3/ENTPD3

T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for for immunohistochemistry starting at 5 μg/mL and immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of T-cadherin in 3T3 lysate with T-cadherin antibody at (A) 0.5 and (B) 1 μg/mL.

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Immunofluorescence of T-cadherin in K562 cells with T-cadherin antibody at 20 μg/mL.

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Immunofluorescence of T-cadherin in 3T3 cells with T-cadherin antibody at 2 μg/mL.

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Immunohistochemistry of T cadherin in mouse brain tissue with T cadherin Antibody at 5 μg/mL.

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Immunofluorescence of T cadherin in mouse brain tissue with T cadherin Antibody at 20 μg/mL.

Green: T-cadherin antibody (A10606)
Red: Phylloidin staining
Blue: DAPI staining

Gene/Protein Information For ENTPD3 (Source: Uniprot.org, NCBI)

Alternative Names

ATPDase; CD39 antigen-like 3; CD39L3; CD39L3EC 3.6.1.5; CD39-like 3; EC 3.6.1; Ecto-apyrase 3; Ecto-ATP diphosphohydrolase 3; Ecto-ATPase 3; Ecto-ATPDase 3; ectonucleoside triphosphate diphosphohydrolase 3; ENTPD3; FLJ93839; HB6; HB6NTPDase 3; NTPDase-3 ENTPD3 CD39L3, HB6, NTPDase-3 ectonucleoside triphosphate diphosphohydrolase 3 ectonucleoside triphosphate diphosphohydrolase 3|CD39 antigen-like 3|NTPDase 3|ecto-ATP diphosphohydrolase 3|ecto-ATPDase 3|ecto-ATPase 3|ecto-apyrase 3

For more info on ENTPD3, check out the ENTPD3 Infographic

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In this infographic, you will see the following information for ENTPD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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