Product Info Summary
SKU: | A14692 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Synaptogyrin-3 SYNGR3 Antibody
View all Synaptogyrin 3 Antibodies
SKU/Catalog Number
A14692
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Synaptogyrin-3 SYNGR3 Antibody (Catalog # A14692). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SYNGR3 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Synaptogyrin-3 SYNGR3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14692)
Host
Rabbit
Contents
SYNGR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SYNGR3 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SYNGR3. The immunogen is located within the last 50 amino acids of SYNGR3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
DISP2 antibody is human specific. At least two isoforms of Disp2 are known to exist. DISP2 antibody is predicted to not cross-react with Disp1 or Disp3.
Reactive Species
A14692 is reactive to SYNGR3 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
24555 MW
Background of Synaptogyrin 3
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. SYNGR3 is involved in the positive regulation of dopamine transporter activity and facilitates the physical and functional interactions of the transporter with the dopamine vesicular storage system, allowing a more efficient loading of the vesicles with extracellular dopamine after release.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A14692 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SYNGR3 antibody can be used for detection of SYNGR3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SYNGR3 in mouse brain tissue lysate with SYNGR3 antibody at (A) 1 and (B) 2 μg/mL .
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Immunohistochemistry of SYNGR3 in rat brain tissue with SYNGR3 antibody at 2.5 μg/mL.
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Immunofluorescence of SYNGR3 in Rat Brain cells with SYNGR3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SYNGR3 (Source: Uniprot.org, NCBI)
Gene Name
SYNGR3
Full Name
Synaptogyrin-3
Weight
24555 MW
Superfamily
synaptogyrin family
Alternative Names
Synaptogyrin-3 SYNGR3 synaptogyrin 3 synaptogyrin-3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SYNGR3, check out the SYNGR3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SYNGR3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Synaptogyrin-3 SYNGR3 Antibody (A14692)
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