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Product Info Summary
| SKU: | A30032 |
|---|---|
| Size: | 50 µl |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-Survivin birc5.1-a Antibody
SKU/Catalog Number
A30032
Size
50 µl
Form
Liquid
Description
Boster Bio Anti-Survivin birc5.1-a Antibody (Catalog# A30032). Tested in IP, IHC, WB application(s). This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Cite This Product
Anti-Survivin birc5.1-a Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30032)
Host
Rabbit
Contents
50 μl sera
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A Full-length recombinant protein of human Survivin
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A30032 is reactive to BIRC5 in Human, Mouse, Rat
Applications
A30032 is guaranteed for IP, IHC, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
18686 MW
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000-1:2000
IHC (paraffin): 1:1000-1:5000
IHC (frozen): Users should optimize
IP: 1:50-1:200
Validation Images & Assay Conditions
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Immunohistochemical analysis of Survivin in a formalin-fixed, paraffin-embedded human brain tissue microarray using primary antibody dilution ratio of 1:2000. A. Differential expression of Survivin in brain tumors from six different patients. A1-A3, high magnification from A. A1, gemistocytic astrocytoma. A2, medulloblastoma. A3, choroid plexus papilloma. Hematoxylin-eosin counterstain.
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Immunohistochemical analysis of Survivin in formalin-fixed, paraffin-embedded human prostate and breast cancer using primary antibody dilution ratio of 1:2000. A and A1, prostate cancer at low and high magnification, respectively. B and B1, breast cancer. B1 is a high magnification of an area of metastasis. Hematoxylin-eosin counterstain.
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Western blot analysis of Survivin using primary antibody dilution ratio of 1:2000. Survivin was detected in the two tumor cell lines, Jurkat (T cell lymphoma) and RS11846 (non-Hodgkin's lymphoma), but not in lysates from normal tissues. Survivin RP, full-length recombiant human survivin protein was used as a positive control.
Protein Target Info & Infographic
Gene/Protein Information For BIRC5 (Source: Uniprot.org, NCBI)
Gene Name
BIRC5
Full Name
Baculoviral IAP repeat-containing protein 5
Weight
18686 MW
Superfamily
IAP family
Alternative Names
API4; apoptosis inhibitor 4; Apoptosis inhibitor survivin; baculoviral IAP repeat-containing 5; Baculoviral IAP Repeat-Containing Protein 5; BIRC5; EPR-1; IAP4; survivin variant 3 alpha; Survivin BIRC5 API4, EPR-1 baculoviral IAP repeat containing 5 baculoviral IAP repeat-containing protein 5|apoptosis inhibitor 4|apoptosis inhibitor survivin|survivin variant 3 alpha
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BIRC5, check out the BIRC5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BIRC5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Survivin birc5.1-a Antibody (A30032)
Hello CJ!
A30032 has been cited in 9 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Reactive Oxygen Species Mediate Isoalantolactone-Induced Apoptosis in Human Prostate Cancer Cells
Transcriptome analysis of Spodoptera frugiperda Sf9 cells reveals putative apoptosis-related genes and a preliminary apoptosis mechanism induced by azadirachtin
Insight into the negative impact of ionic liquid: A cytotoxicity mechanism of 1-methyl-3-octylimidazolium bromide
Prognostic significance of Survivin and CD44v6 in laryngeal cancer surgical margins
Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients
Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients
Loss of cytoplasmic survivin expression is an independent predictor of poor prognosis in radically operated prostate cancer patients
Chen Xm, Xie Xb, Zhao Q, Wang F, Bai Y, Yin Jq, Jiang H, Xie Xl, Jia Q, Huang G. Mol Med Rep. 2015 Jan;11(1):105-12. Doi: 10.3892/Mmr.2014.2733. Epub 2014 Oct 21. Ampelopsin Induces Apoptosis By Regulating Multiple C-Myc/S-Phase Kinase-Associated ...
Lu Yh, Wang K, He R, Xi T. Cancer Biother Radiopharm. 2008 Dec;23(6):727-34. Doi: 10.1089/Cbr.2008.0503. Knockdown Of Survivin And Upregulation Of P53 Gene Expression By Small Interfering Rna Induces Apoptosis In Human Gastric Carcinoma Cell Line ...
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