Data

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Key=store_id
Key=entity_id, value=47960
Key=attribute_set_id, value=4
Key=type_id, value=simple
Key=sku, value=M00036-2
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2018-12-20 11:47:28
Key=updated_at, value=2024-09-26 00:58:43
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-STAT1 Antibody Picoband® (monoclonal, 12C7)
Key=cj_search_index
Key=publication_count, value=5
Key=qty_in_warehouses
Key=is_recurring, value=No
Key=visibility, value=Catalog, Search
Key=tax_class_id, value=Taxable Goods
Key=featured, value=No
Key=featured_image, value=Yes
Key=fb_product, value=
Key=custom_product_page, value=No
Key=free_shipping, value=No
Key=template, value=antibodies
Key=host, value=Mouse
Key=googleshopping_exclude, value=No
Key=yoast_keyword_score, value=-1325
Key=yoast_content_score, value=30
Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-STAT1 Antibody Picoband® (monoclonal, 12C7)
Key=meta_description, value=Boster Bio Anti-STAT1 Antibody Picoband® (monoclonal, 12C7) catalog # M00036-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. Supplied as 100μg/vial in Lyophilized form antibody.
Key=image, value=no_selection
Key=small_image, value=no_selection
Key=thumbnail, value=no_selection
Key=url_key, value=anti-stat1-picoband-trade-antibody-monoclonal-m00036-2-boster
Key=url_path, value=anti-stat1-picoband-trade-antibody-monoclonal-m00036-2-boster
Key=options_container, value=Product Info Column
Key=msrp_display_actual_price_type, value=
Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Lymphocyte antigen 6A-2/6E-1
Key=gene_full_name, value=signal transducer and activator of transcription 1, 91kDa
Key=uniprot_id, value=P42224
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500μg/ml.
Key=sensitivity
Key=applications, value=Flow Cytometry, IF, IHC, ICC, WB
Key=reactivity, value=Human, Monkey
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P) and ICC.
Key=clone_number, value=12C7
Key=predicted_reactivity
Key=source_company, value=Boster M00036-2
Key=isotype, value=Mouse IgG1
Key=molecular_weight, value=14377 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies, Monoclonal Antibodies
Key=research_category, value=Cancer, Epigenetics and Nuclear Signaling, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway, Transcription
Key=clonality, value=Monoclonal
Key=swatch_image, value=/a/3/a34007-septin2-primary-antibodies-wb-testing-1.jpg
Key=rating_value, value=98.6
Key=review_count, value=14
Key=phospho_site
Key=mp_exclude_sitemap, value=Yes
Key=yoast_facebook_image, value=/a/3/a34007-septin2-primary-antibodies-wb-testing-1.jpg
Key=yoast_twitter_image, value=/a/3/a34007-septin2-primary-antibodies-wb-testing-1.jpg
Key=cj_related_products, value=Hepatitis C:A01025-Dyl488|RP1057|A01246-2^Janiceps:PA1707|PA1508|EK1436
Key=description, value=Boster Bio Anti-STAT1 Antibody Picoband® (monoclonal, 12C7) catalog # M00036-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-STAT1 Antibody Picoband® (monoclonal, 12C7) catalog # M00036-2. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-STAT1 Antibody Picoband® (monoclonal, 12C7)
Key=contents, value=Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Key=gene_name, value=STAT1
Key=synonyms, value=Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; STAT1
Key=application_details, value=Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
Immunocytochemistry/Immunofluorescence, 2μg/ml
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells

Key=subcellular_localization, value=Nucleus. Cytoplasm.
Key=tissue_specificity, value= Expressed in several hair follicle cell types: basal and peripheral matrix cells, and cells of the outer and inner root sheaths. Expressed in colon. Present in cortical neurons (at protein level).
Key=application_notes, value=Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 134474|sc 52601
Key=immunogen, value=E.coli-derived human STAT1 recombinant protein (Position: S2-A230). Human STAT1 shares 91.2% amino acid (aa) sequence identity with mouse STAT1.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=91 kDa
Key=custom_attribute_2, value=WB: human Hela whole cell, human placenta tissue, human 22RV1 whole cellmonkey COS-7 whole cell, human SW620 whole cell, human HepG2 whole cell, human PANC-1 whole cell
IHC: human intestinal cancer tissue, human intestinal cancer tissue, human mammary cancer tissue, human tonsil tissue
FCM: A431 cell
Key=protein_function, value=Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases leads to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN-stimulated genes (ISG), which drive the cell in an antiviral state. In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated. It then forms a homodimer termed IFN-gamma-activated factor (GAF), migrates into the nucleus and binds to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. Becomes activated in response to KITLG/SCF and KIT signaling. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
Key=options
Key=media_gallery
Key=extension_attributes
Key=tier_price
Key=tier_price_changed
Key=category_ids
Key=quantity_and_stock_status
Key=is_salable
Key=website_ids
Key=request_path
Key=rating_summary
Key=_cache_instance_store_filter
Key=media_gallery_images