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STAT1 Antibodies
AND STAT1 ELISA kits, STAT1 Proteins
Many biological assays use antibodies to detect STAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STAT1 antibodies...
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STAT1 Infographic by Boster Bio
All STAT1 Products
Product
Figures
Specificity
Applications
Price
Anti-STAT1 Antibody Picoband®
7 Citations 5 Q&As
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # PB9510
100 μg/vial
Cat # PB9510
100 μg/vial
Anti-STAT1 Antibody Picoband®
4 Citations 16 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PA1075
100 μg/vial
Cat # PA1075
100 μg/vial
Anti-STAT1 Antibody Picoband®
4 Citations 4 Q&As
Human, Mouse
Flow Cytometry, WB
$370
Cat # PA1508
100 μg/vial
Cat # PA1508
100 μg/vial
Anti-STAT1 Antibody Picoband®
3 Citations 16 Q&As
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00036-2
100 μg/vial
Cat # A00036-2
100 μg/vial
Anti-Phospho-STAT1 (Y701) Rabbit Monoclonal Antibody
2 Citations 4 Q&As
Human
WB
$370
Cat # P00036
100 μl
Cat # P00036
100 μl
Anti-STAT1 Rabbit Monoclonal Antibody
2 Citations 16 Q&As
Human, Mouse
Flow Cytometry, IP, IHC, WB
$370
Cat # M00036-1
100 μl
Cat # M00036-1
100 μl
Anti-STAT1 alpha Rabbit Monoclonal Antibody
2 Citations 13 Q&As
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00036
100 μl
Cat # M00036
100 μl
Anti-STAT1 Antibody Picoband® (monoclonal, 12C7)
5 Citations 15 Q&As
Human, Monkey
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00036-2
100 μg/vial
Cat # M00036-2
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1541
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1541
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2513
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2513
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2514
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2514
1 kit, containing two 96-well plates and all necessary reagents
Functional Assay
$5040
Cat # RC1012
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Cat # RC1012
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Functional Assay
$5040
Cat # RC1013
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Cat # RC1013
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
STAT1 Overview
Facts about Signal transducer and activator of transcription 1-alpha/beta.
Signal transducer and activator of transcription 1-alpha/beta (STAT1)
Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. After type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signaling via protein kinases contributes to activation of Jak kinases (TYK2 and JAK1) and to tyrosine phosphorylation of STAT1 and STAT2.
The phosphorylated STATs dimerize and associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus (PubMed:28753426). ISGF3 binds to the IFN stimulated response element (ISRE) to trigger the transcription of IFN-stimulated genes (ISG), which drive the mobile in an antiviral state.
Gene Information
| Human | |
|---|---|
| Gene Name: | STAT1 |
| Uniprot: | P42224 |
| Entrez: | 6772 |
Family
| Belongs to: |
|---|
| transcription factor STAT family |
Alternative Names
CANDF7; DKFZp686B04100; ISGF-3; ISGF-3,91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription-1; STAT1; STAT91
Molecular Weight
Mass (kDA):
87.335 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.2 |
| Sequence: | 2; NC_000002.12 (190968989..191014250, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to IFN-gamma and signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4 (PubMed:15322115). Monomethylation at Lys-525 is required for phosphorylation at Tyr-701 and translocation into the nucleus (PubMed:28753426). Translocates into the nucleus in response to interferon-beta stimulation (PubMed:26479788).
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Janiceps
- Virus Diseases
- Leukemia
- Carcinoma
- Infective Disorder
- Hepatitis
- Cell Transformation, Neoplastic
- Autoimmune Reaction
- Tissue Adhesions
- Liver Carcinoma
Interacting Proteins
- DDB1
- DDX58
- E2F1
- EGFR
- EIF1AD
- ERBB2
- FOS
- IFNAR1
- IFNAR2
- IFNGR1
Pathways
- Pathogenesis
- Immune Response
- Cell Proliferation
- Secretion
- Cell Growth
- Cell Death
- Localization
- Cell Cycle
- Inflammatory Response
- Cell Differentiation
- Cytokine Production
- Viral Replication
- Cell Activation
PTMs
- Phosphorylation
- Dephosphorylation
- Methylation
- Cleavage
- Acetylation
- Ubiquitination
- Sumoylation
- Nitration
- Reduction
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STAT1
bosterbio.com/bosterbio-gene-info-cards/STAT1
References
PMID: 1502203 by Schindler C., et al. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
PMID: 7885841 by Yan R., et al. The genomic structure of the STAT genes: multiple exons in coincident sites in Stat1 and Stat2.
10 Publications of Boster STAT1 Antibodies & ELISA Kits
- PubMed ID: 10.3748/wjg.v13.i30.4080, Hepatitis C Virus non-structural 5A abrogates signal transducer and activator of...
- PubMed ID: 10.3390/ijms18030570, Blockage of Glyoxalase I Inhibits Colorectal Tumorigenesis and Tumor Growth via ...
- PubMed ID: 10.1007/s00467-009-1163-4, Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental...
- PubMed ID: 10.1007/s00403-008-0872-z, Effects of acitretin on proliferative inhibition and RANTES production of HaCaT ...
- PubMed ID: , Death signal transduction induced by co-immobilized TNF-α plus IFN-γ and the d...
- PubMed ID: 31731208, Gao Y,Gui F,Li D,Zhang R,Sun Q,Guo X.Fluoride regulates the expression of extrac...
- PubMed ID: 28903386, Synergistic inhibition of colon cancer growth by the combination of methylglyoxa...
- PubMed ID: 17696225, Hepatitis C virus non-structural 5A abrogates signal transducer and activator of...
- PubMed ID: 29393353, Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK...
- PubMed ID: 24625919, Song Cg, Yang X, Min Lq, Liu Cx, Zhao Cs. Neuro Endocrinol Lett. 2014;35(1):68-7...
*More publications can be found for each product on its corresponding product page