Anti-SOCS2 Antibody Picoband®

Product Name

Anti-SOCS2 Antibody Picoband®

View all SOCS-2 Antibodies

SKU/Catalog Number

PB9400

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-SOCS2 Antibody Picoband® catalog # PB9400. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SOCS2 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9400)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human SOCS2 recombinant protein (Position: R96-V198). Human SOCS2 shares 96.1% and 95.1% amino acid (aa) sequence identity with mouse and rat SOCS2, respectively.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9400 is reactive to SOCS2 in Human, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

22 kDa

Calculated molecular weight

22172 MW

Background of SOCS-2

Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PB9400 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat

Positive Control

WB: PC-12 Whole Cell, SW620 Whole Cell, HELA Whole Cell, MCF-7 Whole Cell

Validation Images & Assay Conditions

Gene/Protein Information For SOCS2 (Source: Uniprot.org, NCBI)

Alternative Names

Suppressor of cytokine signaling 2;SOCS-2;Cytokine-inducible SH2 protein 2;CIS-2;STAT-induced STAT inhibitor 2;SSI-2;SOCS2;CIS2, SSI2, STATI2; SOCS2 CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2 suppressor of cytokine signaling 2 suppressor of cytokine signaling 2|CIS-2|STAT-induced STAT inhibitor 2|cytokine-inducible SH2 protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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