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Product Info Summary
| SKU: | A11967 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLIT and NTRK-like protein 2 Slitrk2 Antibody
SKU/Catalog Number
A11967
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLIT and NTRK-like protein 2 Slitrk2 Antibody (Catalog # A11967). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Slitrk2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLIT and NTRK-like protein 2 Slitrk2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A11967)
Host
Rabbit
Contents
Slitrk2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Slitrk2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human Slitrk2. The immunogen is located within amino acids 770 - 820 of Slitrk2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Reactive Species
A11967 is reactive to SLITRK2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
95404 MW
Background of SLITRK2
SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A11967 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Slitrk2 antibody can be used for detection of Slitrk2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Slitrk2 in rat brain tissue lysate with Slitrk2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunohistochemistry of Slitrk2 in human brain tissue with Slitrk2 antibody at 2.5 μg/mL.
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Immunofluorescence of Slitrk2 in Human Brain cells with Slitrk2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLITRK2 (Source: Uniprot.org, NCBI)
Gene Name
SLITRK2
Full Name
SLIT and NTRK-like protein 2
Weight
95404 MW
Superfamily
SLITRK family
Alternative Names
CXorf2, SLITL1, CXorf2, KIAA1854, UNQ9197/PRO34756, SLIT and NTRK-like protein 2 SLITRK2 CXorf1, CXorf2, SLITL1, TMEM257 SLIT and NTRK like family member 2 SLIT and NTRK-like protein 2|slit and trk like gene 2|slit-like 1|transmembrane protein 257
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLITRK2, check out the SLITRK2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLITRK2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLIT and NTRK-like protein 2 Slitrk2 Antibody (A11967)
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