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Product Info Summary
| SKU: | A12449 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-SLC35D2 Antibody
SKU/Catalog Number
A12449
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLC35D2 Antibody (Catalog # A12449). Tested in ELISA, WB, ICC applications. This antibody reacts with Human.
Storage & Handling
SLC35D2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLC35D2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12449)
Host
Rabbit
Contents
SLC35D2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SLC35D2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human SLC35D2. The immunogen is located within the last 50 amino acids of SLC35D2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of SLC35D2 are known to exist; this antibody will recognize both isoforms. SLC35D2 antibody is predicted to not cross-react with SLC35D1 or SLC35D3.
Reactive Species
A12449 is reactive to SLC35D2 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
36673 MW
Background of SLC35D2
The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The role of the ER-resident SLC family member SLC35D2 is to transport both UDP-glucuronic acid and UDP-N-acetylgalactosamine. Its overexpression in transfected cells modulated cell surface heparin sulfate expression, suggesting that SLC35D2 is involved in heparin sulfate synthesis. SLC35D2-overexpressing cells also showed increased constitutive and hypotonic stress-stimulated release of UDP-GlcNAc, suggesting that SLC35D2 may be involved in UDP-sugar release and cell signaling.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12449 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLC35D2 antibody can be used for detection of SLC35D2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLC35D2 in HeLa cell lysate with SLC35D2 antibody at (A) 1 and (B) 2 μg/mL.
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Immunocytochemistry of SLC35D2 in HeLa cells with SLC35D2 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC35D2 (Source: Uniprot.org, NCBI)
Gene Name
SLC35D2
Full Name
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter
Weight
36673 MW
Superfamily
TPT transporter family
Alternative Names
hfrc, HFRC1, SQV7L, UGTrel8, HFRC, UGTREL8, Homolog of Fringe connection protein 1 SLC35D2 HFRC1, SQV7L, UGTrel8, hfrc solute carrier family 35 member D2 UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter|SQV7-like protein|UDP-N-acetylglucosamine transporter|UDP-galactose transporter-related protein 8|fringe connection|homolog of Fringe connection protein 1|solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC35D2, check out the SLC35D2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC35D2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLC35D2 Antibody (A12449)
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