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Product Info Summary
| SKU: | A02058 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLC29A1 Antibody
SKU/Catalog Number
A02058
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLC29A1 Antibody (Catalog # A02058). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human.
Storage & Handling
SLC29A1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-SLC29A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02058)
Host
Rabbit
Contents
SLC29A1 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SLC29A1 antibody was raised against a 17 amino acid peptide near the center of human SLC29A1. The immunogen is located within amino acids 240 - 290 of SLC29A1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SLC29A1 antibody is human specific. SLC29A1 antibody is predicted to not cross-react with other SLC29 proteins.
Reactive Species
A02058 is reactive to SLC29A1 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
50219 MW
Background of ENT1
SLC29A1 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A1 is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A1 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02058 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLC29A1 antibody can be used for detection of SLC29A1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLC29A1 in human ovary tissue lysate with SLC29A1 antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of SLC29A1 in human ovary tissue with SLC29A1 antibody at 5 μg/mL.
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Immunofluorescence of SLC29A1 in human ovary tissue with SLC29A1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLC29A1 (Source: Uniprot.org, NCBI)
Gene Name
SLC29A1
Full Name
Equilibrative nucleoside transporter 1
Weight
50219 MW
Superfamily
SLC29A/ENT transporter (TC 2.A.57) family
Alternative Names
Solute carrier family 29 member 1, Equilibrative nucleoside transporter 1, ENT1 SLC29A1 ENT1 solute carrier family 29 member 1 (Augustine blood group) equilibrative nucleoside transporter 1|equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter|nucleoside transporter, es-type|solute carrier family 29 (equilibrative nucleoside transporter), member 1|solute carrier family 29 (nucleoside transporters), member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC29A1, check out the SLC29A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC29A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLC29A1 Antibody (A02058)
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