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Product Info Summary
| SKU: | A03988 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-SLAMF1 Antibody
View all SLAM/CD150 Antibodies
SKU/Catalog Number
A03988
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SLAMF1 Antibody (Catalog # A03988). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SLAMF1 antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SLAMF1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03988)
Host
Rabbit
Contents
SLAMF1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SLAMF1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human SLAMF1. The immunogen is located within amino acids 30 - 80 of SLAMF1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
4 isoforms of SLAMF1 are known to exist; this antibody will is predicted to recognize all 4 isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
Reactive Species
A03988 is reactive to SLAMF1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
37231 MW
Background of SLAM/CD150
The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03988 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SLAMF1 antibody can be used for detection of SLAMF1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SLAMF1 in rat colon tissue lysate with SLAMF1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of SLAMF1 in human colon tissue with SLAMF1 antibody at 5 μg/mL.
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Immunofluorescence of SLAMF1 in human colon tissue with SLAMF1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SLAMF1 (Source: Uniprot.org, NCBI)
Gene Name
SLAMF1
Full Name
Signaling lymphocytic activation molecule
Weight
37231 MW
Alternative Names
SLAM, CD150, CDw150, SLAM, Signaling lymphocytic activation molecule SLAMF1 CD150, CDw150, SLAM signaling lymphocytic activation molecule family member 1 signaling lymphocytic activation molecule|IPO-3|SLAM family member 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLAMF1, check out the SLAMF1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLAMF1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SLAMF1 Antibody (A03988)
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