Click image to see more details
Product Info Summary
| SKU: | A00611 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Chicken |
| Application: | ELISA, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-SIRT6 Antibody
SKU/Catalog Number
A00611
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-SIRT6 Antibody (Catalog # A00611). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SIRT6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-SIRT6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00611)
Host
Chicken
Contents
SIRT6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgY
Immunogen
SIRT6 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SIRT6. The immunogen is located within the last 50 amino acids of SIRT6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00611 is reactive to SIRT6 in Human, Mouse, Rat
Reconstitution
Calculated molecular weight
39119 MW
Background of Sirt6
The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00611 is guaranteed for ELISA, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SIRT6 antibody can be used for detection of SIRT6 by Western blot at 0.5 - 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of SIRT6 in HeLa cell lysate with SIRT6 antibody at (A) 0.5 and (B) 1 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SIRT6 (Source: Uniprot.org, NCBI)
Gene Name
SIRT6
Full Name
NAD-dependent protein deacetylase sirtuin-6
Weight
39119 MW
Superfamily
sirtuin family
Alternative Names
SIR2L6, SIR2L6, NAD-dependent protein deacetylase sirtuin-6, Regulatory protein SIR2 homolog 6 Sirt6|2810449N18Rik, AI043036, Sir2l6|sirtuin 6|NAD-dependent protein deacetylase sirtuin-6|NAD-dependent deacetylase sirtuin-6|SIR2-like protein 6|regulatory protein SIR2 homolog 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SIRT6, check out the SIRT6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SIRT6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SIRT6 Antibody (A00611)
Hello CJ!
No publications found for A00611
*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-SIRT6 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-SIRT6 Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
