Product Info Summary
SKU: | A01790-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-SHIP-2 INPPL1 Antibody
View all SHIP2/INPPL1 Antibodies
SKU/Catalog Number
A01790-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SHIP-2 INPPL1 Antibody catalog # A01790-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SHIP-2 INPPL1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01790-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human SHIP-2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01790-1 is reactive to INPPL1 in Human, Mouse, Rat
Applications
A01790-1 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
138599 MW
Background of SHIP2/INPPL1
Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
Quaderi N.A., Nat. Genet. 17:285-291(1997).
Perry J., Hum. Mol. Genet. 7:299-305(1998).
Van den Veyver I.B., Genomics 51:251-261(1998).<
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
Validation Images & Assay Conditions
![a01790 1 anti ship 2 inppl1 antibody ihc testing 2 a01790 1 anti ship 2 inppl1 antibody ihc testing 2](https://www.bosterbio.com/media/catalog/product/a/0/a01790-1-anti-ship-2-inppl1-antibody-ihc-testing-2.jpg)
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Figure 2. Immunohistochemistry validation of INPPL1 using Anti-SHIP-2 INPPL1 Antibody (A01790-1).
Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Brain![a01790 1 anti ship 2 inppl1 antibody ihc testing 3 a01790 1 anti ship 2 inppl1 antibody ihc testing 3](https://www.bosterbio.com/media/catalog/product/a/0/a01790-1-anti-ship-2-inppl1-antibody-ihc-testing-3.jpg)
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Figure 3. Immunohistochemistry validation of INPPL1 using Anti-SHIP-2 INPPL1 Antibody (A01790-1).
Immunohistochemistry (IHC) analysis of paraffin-embedded Mouse Brain![a01790 1 anti ship 2 inppl1 antibody wb testing 1 a01790 1 anti ship 2 inppl1 antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a01790-1-anti-ship-2-inppl1-antibody-wb-testing-1.jpg)
Click image to see more details
Figure 1. Western blotting validation for Anti-SHIP-2 INPPL1 Antibody A01790-1
Western Blot (WB) analysis of HepG2 cells using SHIP-2 polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For INPPL1 (Source: Uniprot.org, NCBI)
Gene Name
INPPL1
Full Name
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Weight
138599 MW
Superfamily
inositol 1,4,5-trisphosphate 5-phosphatase family
Alternative Names
EC 3.1.3; EC 3.1.3.n1; inositol polyphosphate phosphatase-like 1; Inositol polyphosphate phosphatase-like protein 1; INPPL1; INPPL-1; phosphatidylinositol-34,5-trisphosphate 5-phosphatase 2; Protein 51C; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SHIP2; SHIP-2; SHIP251C protein INPPL1 OPSMD, SHIP2 inositol polyphosphate phosphatase like 1 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2|51C protein|INPPL-1|SH2 domain-containing inositol-5-phosphatase 2|SHIP-2|protein 51C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on INPPL1, check out the INPPL1 Infographic
![INPPL1 infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for INPPL1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SHIP-2 INPPL1 Antibody (A01790-1)
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