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Product Info Summary
| SKU: | A30763-1 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-SGOL2 Antibody (Center)
SKU/Catalog Number
A30763-1
Size
80 µl
Description
Boster Bio Anti-SGOL2 Antibody (Center) (Catalog # A30763-1). Tested in WB application(s). This antibody reacts with Human.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-SGOL2 Antibody (Center) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A30763-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A30763-1 is reactive to SGO2 in Human
Reconstitution
Calculated molecular weight
144739 Da
Background of SGO2
Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A30763-1 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
Validation Images & Assay Conditions
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SGOL2 Antibody (Center) western blot analysis in U-937 cell line lysates (35ug/lane).This demonstrates the SGOL2 antibody detected the SGOL2 protein (arrow).
Protein Target Info & Infographic
Gene/Protein Information For SGO2 (Source: Uniprot.org, NCBI)
Gene Name
SGO2
Full Name
Shugoshin 2
Weight
144739 Da
Superfamily
shugoshin family
Alternative Names
Shugoshin-like 2, Shugoshin-2, Sgo2, Tripin, SGOL2 SGO2 SGOL2, TRIPIN shugoshin 2 shugoshin 2|shugoshin-like 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SGO2, check out the SGO2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SGO2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SGOL2 Antibody (Center) (A30763-1)
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