Anti-SENP8 (T191) Antibody

Product Name

Anti-SENP8 (T191) Antibody

View all NEDP1/SENP8 Antibodies

SKU/Catalog Number

A07848T191

Size

100ul

Form

Liquid

Description

Boster Bio Anti-SENP8 (T191) Antibody catalog # A07848T191. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SENP8 (T191) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07848T191)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from Internal of human SENP8.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A07848T191 is reactive to Senp8 in Human, Mouse, Rat

Applications

A07848T191 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

24107 MW

Background of NEDP1/SENP8

Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.

Tudeviin Gan-Erdene, J. Biol. Chem., Aug 2003; 278: 28892 - 28900.
Debaditya Mukhopadhyay, J. Cell Biol., Sep 2006; 174: 939 - 949.
Thomas Colby, Plant Physiology, Sep 2006; 142: 318 - 332.
Joris Hemelaar, Mol. Cell. Biol., Jan 2004; 24: 84 - 95.<

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC: 1:50-1:200

Validation Images & Assay Conditions

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Figure 1. Immunohistochemistry validation of SENP8 using Anti-SENP8 (T191) Antibody (A07848T191).

Immunohistochemistry (IHC) analyzes of SENP8 (T191) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
For more protocol information of IHC

Gene/Protein Information For Senp8 (Source: Uniprot.org, NCBI)

Alternative Names

DEN1; DEN1deneddylase-1; deneddylase 1; Deneddylase-1; EC 3.4.22.-; HsT17512; NEDD8-specific protease 1; NEDP1; NEDP1NEDD8 specific-protease cysteine 2; Protease, cysteine 2; protease, cysteine, 2 (NEDD8 specific); PRSC2; SENP8; Sentrin/SUMO-specific protease SENP8; sentrin-specific protease 8; SUMO sentrin specific protease family member 8; SUMO/sentrin specific peptidase family member 8; SUMO/sentrin specific protease family member 8 Senp8|9130010J17Rik, AU020827, Den, Den1, Ned, Nedp1, Pr, Prsc2|SUMO/sentrin specific peptidase 8|sentrin-specific protease 8|NEDD8-specific protease 1|SUMO/sentrin specific protease 8|SUMO/sentrin specific protease family member 8|deneddylase-1|protease, cysteine, 2 (NEDD8 specific)|sentrin/SUMO-specific protease SENP8

For more info on Senp8, check out the Senp8 Infographic

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In this infographic, you will see the following information for Senp8: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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