Anti-Secretogranin-1 CHGB Antibody

Product Name

Anti-Secretogranin-1 CHGB Antibody

View all Chromogranin B Antibodies

SKU/Catalog Number

A04073

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Secretogranin-1 CHGB Antibody catalog # A04073. Tested in WB applications. This antibody reacts with Human,Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Secretogranin-1 CHGB Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04073)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human MRC2.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A04073 is reactive to CHGB in Human, Mouse

Applications

A04073 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

78276 MW

Background of Chromogranin B

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).

Behrendt N., J. Biol. Chem. 275:1993-2002(2000).
Sheikh H., J. Cell Sci. 113:1021-1032(2000).
Howard M.J., J. Biol. Chem. 277:32320-32331(2002).<

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:100-1:500

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-Secretogranin-1 CHGB Antibody A04073

Western blot analysis of extracts of various cells

Gene/Protein Information For CHGB (Source: Uniprot.org, NCBI)

Alternative Names

CgB; CHGB; chromogranin B (secretogranin 1); Chromogranin B; Chromogranin-B; SCG1; SCG1sgI; secretogranin B; Secretogranin I; secretogranin-1; SgI CHGB SCG1 chromogranin B secretogranin-1|cgB|secretogranin B|secretogranin I|sgI

For more info on CHGB, check out the CHGB Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CHGB: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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