Anti-GGH/Gamma Glutamyl Hydrolase Antibody

Product Name

Anti-GGH/Gamma Glutamyl Hydrolase Antibody

View all gamma-glutamyl hydrolase Antibodies

SKU/Catalog Number

A03161

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-GGH/Gamma Glutamyl Hydrolase Antibody (Catalog # A03161). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GGH/Gamma Glutamyl Hydrolase Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03161)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human GGH.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03161 is reactive to GGH in Human, Mouse

Applications

A03161 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

35964 MW

Background of gamma-glutamyl hydrolase

Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.

Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996).
Yin D., Gene 238:463-470(1999).
Basrur V., J. Proteome Res. 2:69-79(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

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Western blot analysis of extracts from RAW264.7 cells, using GGH antibody A03161.

Gene/Protein Information For GGH (Source: Uniprot.org, NCBI)

Alternative Names

Conjugase; EC 3.4.19.9; gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); gamma-glutamyl hydrolase; Gamma-Glu-X carboxypeptidase; GH GGH GH gamma-glutamyl hydrolase gamma-glutamyl hydrolase|gamma-Glu-X carboxypeptidase|gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)

For more info on GGH, check out the GGH Infographic

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In this infographic, you will see the following information for GGH: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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