Product Info Summary
SKU: | A06985 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF, WB |
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Product info
Product Name
Anti-SEC24D Antibody
SKU/Catalog Number
A06985
Size
100ul
Form
Liquid
Description
Boster Bio Anti-SEC24D Antibody catalog # A06985. Tested in WB,IF applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-SEC24D Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06985)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
A synthetic peptide corresponding to residues in Human RGMB
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A06985 is reactive to SEC24D in Human
Applications
A06985 is guaranteed for IF, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
113010 MW
Background of SEC24D
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Celeste A.J., Submitted (OCT-1998) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 434:724-731(2005).
Mazerbourg S., J. Biol. Chem. 280:32122-32132(2005).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IF: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-SEC24D Antibody A06985
Western blot analysis of extracts of various cell linesProtein Target Info & Infographic
Gene/Protein Information For SEC24D (Source: Uniprot.org, NCBI)
Gene Name
SEC24D
Full Name
Protein transport protein Sec24D
Weight
113010 MW
Superfamily
SEC23/SEC24 family
Alternative Names
FLJ43974; KIAA0755member D; SEC24 family, member D (S. cerevisiae); SEC24 related gene family, member D SEC24D CLCRP2 SEC24 homolog D, COPII coat complex component protein transport protein Sec24D|SEC24 related gene family, member D|SEC24-related protein D
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SEC24D, check out the SEC24D Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SEC24D: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-SEC24D Antibody (A06985)
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No publications found for A06985
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