Anti-SC6A3 SLC6A3 Antibody

Product Name

Anti-SC6A3 SLC6A3 Antibody

View all SLC6A3/DAT1 Antibodies

SKU/Catalog Number

A00369

Size

100ul

Form

Liquid

Description

Boster Bio Anti-SC6A3 SLC6A3 Antibody catalog # A00369. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-SC6A3 SLC6A3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00369)

Host

Rabbit

Contents

Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human NOS2 around the phosphorylation site of Y151.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

Does not cross-react with eNOS or nNOS.

Reactive Species

A00369 is reactive to SLC6A3 in Human, Mouse, Rat

Applications

A00369 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

68495 MW

Background of SLC6A3/DAT1

This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

David A. Jans, J. Biol. Chem., Nov 1996; 271: 30781.
Eugene Estella, Diabetes, Aug 2006; 55: 2212 - 2219.
Yong Gu, J. Biol. Chem., May 1996; 271: 10816.
Jiuru Sun, J. Biol. Chem., Nov 1996; 271: 27802.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-2000 ELISA 1:5000-20000

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For SLC6A3 (Source: Uniprot.org, NCBI)

Alternative Names

DA transporter; DAT1; DATDAT1Solute carrier family 6 member 3; SLC6A3; sodium-dependent dopamine transporter; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; VNTR SLC6A3 DAT, DAT1, PKDYS, PKDYS1 solute carrier family 6 member 3 sodium-dependent dopamine transporter|DA transporter|dopamine transporter 1|solute carrier family 6 (neurotransmitter transporter), member 3|solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

For more info on SLC6A3, check out the SLC6A3 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for SLC6A3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the SLC6A3 Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis