Anti-RIP3/RIPK3 Antibody Picoband®

Product Name

Anti-RIP3/RIPK3 Antibody Picoband®

View all RIPK3/RIP3 Antibodies

SKU/Catalog Number

PA2242

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-RIP3/RIPK3 Antibody catalog # PA2242. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RIP3/RIPK3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2242)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human RIP3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2242 is reactive to RIPK3 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

56 kDa, 77 kDa

Calculated molecular weight

56887 MW

Background of RIPK3/RIP3

Receptor-interacting serine/threonine-protein kinase 3 (RIPK3), also known as RIP3 is an enzyme that in humans is encoded by the RIPK3 gene. This gene is mapped to 14q12. The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

PA2242 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human

Positive Control

WB: PANC Cell, SW620 Cell, SKOV-3 Cell, M231 Cell

Validation Images & Assay Conditions

Gene/Protein Information For RIPK3 (Source: Uniprot.org, NCBI)

Alternative Names

Receptor-interacting serine/threonine-protein kinase 3;2.7.11.1;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3;RIPK3;RIP3; RIPK3 RIP3 receptor interacting serine/threonine kinase 3 receptor-interacting serine/threonine-protein kinase 3|RIP-3|RIP-like protein kinase 3|receptor interacting protein 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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