RIPK3 Antibodies

AND RIPK3 ELISA kits, RIPK3 Proteins

Many biological assays use antibodies to detect RIPK3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RIPK3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RIPK3 antibodies...

We validate the specificity of these antibodies to RIPK3 by testing them on tissues known to express RIPK3 positively and negatively. Browse below to find the RIPK3 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RIPK3 Infographic by Boster Bio

All RIPK3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-RIP3/RIPK3 Antibody Picoband®

1 Citations 4 Q&As

Human

$370
Cat # PA2242
100 μg/vial

Anti-RIPK3 Antibody

Human

$299
Cat # M00202
50 µl

Anti-RIP3 (RIPK3) Mouse Monoclonal Antibody [Clone ID: OTI1B3]

Human

IHC, WB

$523
Cat # M00202-1
100 µl

Anti-Phospho-RIP3 (S232) Rabbit Monoclonal Antibody

Mouse, Rat

$370
Cat # M00202S232
100 µl/vial

RIPK3 Overview

Facts about Receptor-interacting serine/threonine-protein kinase 3.

RIPK3 3D structure. Source: alphafold

Receptor-interacting serine/threonine-protein kinase 3 (RIPK3)

Critical for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complicated.

RIPK3 binds to and enhances the action of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes can eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Gene Information

Human
Gene Name:	RIPK3
Uniprot:	Q9Y572
Entrez:	11035

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11.1; Receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; RIP3; RIP-3; RIP3receptor interacting protein 3; RIPK3; RIP-like protein kinase 3

Molecular Weight

Mass (kDA):
56.887 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (24336025..24339991, complement)

Tissue Specificity

Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers.