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Product Info Summary
| SKU: | A03940 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-RILP Antibody
SKU/Catalog Number
A03940
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-RILP Antibody (Catalog # A03940). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
RILP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-RILP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03940)
Host
Rabbit
Contents
RILP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RILP antibody was raised against an 18 amino acid synthetic peptide near the center of human RILP. The immunogen is located within amino acids 110 - 160 of RILP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
Reactive Species
A03940 is reactive to RILP in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
44200 MW
Background of RILP
The Rab interacting lysosomal protein (RILP) is lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. It is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic. Overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell suggesting that RILP may also be involved in the regulation of lysosomal morphology. Other evidence suggests that RILP may play a role in the biogenesis of multivesicular bodies.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03940 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RILP antibody can be used for detection of RILP by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RILP in A20 cell lysate with RILP antibody at 1 μg/mL.
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Immunocytochemistry of RILP in HeLa cells with RILP antibody at 2.5 μg/mL.
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Immunofluorescence of RILP in HeLa cells with RILP antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For RILP (Source: Uniprot.org, NCBI)
Gene Name
RILP
Full Name
Rab-interacting lysosomal protein
Weight
44200 MW
Alternative Names
PP10141, Rab-interacting lysosomal protein RILP PP10141 Rab interacting lysosomal protein rab-interacting lysosomal protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RILP, check out the RILP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RILP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-RILP Antibody (A03940)
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