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Product Info Summary
| SKU: | A05281 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, ICC, WB |
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Product info
Product Name
Anti-Ribonuclease T2 RNASET2 Antibody
SKU/Catalog Number
A05281
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ribonuclease T2 RNASET2 Antibody (Catalog # A05281). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
RNASET2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Ribonuclease T2 RNASET2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05281)
Host
Rabbit
Contents
RNASET2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
RNASET2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human RNASET2. The immunogen is located within the last 50 amino acids of RNASET2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Depending on cell lines or tissues used, other cleavage products may be observed.
Reactive Species
A05281 is reactive to RNASET2 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
29481 MW
Background of RNASET2
RNASET2 is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement, and has been suggested to function as a tumor suppressor protein. Its expression is suppressed in Human T-cell Leukemia Virus type 1 (HTLV-1) infected cells following the binding of the HTLV-1 Tax protein to the RNASET2 promoter. As Adult T-cell leukemia (ATL) is one of the primary diseases caused by HTLV-1 infection, a reduction in the level of RNASET2 by Tax may play a role in ATL development.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05281 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
RNASET2 antibody can be used for detection of FOXRED2 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of RNASET2 in SW480 cell lysate with RNASET2 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunocytochemistry of RNASET2 in SW480 cells with RNASET2 antibody at 2.5 μg/ml.
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Immunofluorescence of RNASET2 in SW480 cells with RNASET2 antibody at 5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For RNASET2 (Source: Uniprot.org, NCBI)
Gene Name
RNASET2
Full Name
Ribonuclease T2
Weight
29481 MW
Superfamily
RNase T2 family
Alternative Names
RNASE6PL, bA514O12.3, RNASE6PL, Ribonuclease T2, Ribonuclease 6 RNASET2 RNASE6PL, bA514O12.3 ribonuclease T2 ribonuclease T2|ribonuclease 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RNASET2, check out the RNASET2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RNASET2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ribonuclease T2 RNASET2 Antibody (A05281)
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