Anti-RGS3 Antibody Picoband®

Product Name

Anti-RGS3 Antibody Picoband®

View all RGS3 Antibodies

SKU/Catalog Number

PA2050

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-RGS3 Antibody catalog # PA2050. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-RGS3 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2050)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of mouse RGS3, identical to the related rat sequence, and different from the related human sequence by two amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2050 is reactive to Rgs3 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

93 kDa

Calculated molecular weight

106219 MW

Background of RGS3

RGS3 (Regulator of G Protein Signaling 3), is a protein that in humans is encoded by the RGS3 gene. Chatterjee et al. (1997) studied RGS3, the largest member of the RGS family then identified. Mouse Pdz-Rgs3 can mediate signaling from the ephrin-B cytoplasmic tail. By radiation hybrid mapping, Chatterjee et al. (1997) assigned the RGS3 gene to chromosome 9q31-q33. Lu et al. (2001) showed that Sdf1, a chemokine with a G protein-coupled receptor, and Bdnf are chemoattractants for cerebellar granule cells, and that Sdf1 chemoattraction is selectively inhibited by soluble ephrin-B receptor. This inhibition could be blocked by a truncated Pdz-Rgs3 protein lacking the RGS domain.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PA2050 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Positive Control

WB: Rat Testis Tissue, Rat Brain Tissue, Rat Spleen Tissue, HELA Cell, U87 Cell,
IHC: Rat Intestine Tissue

Validation Images & Assay Conditions

Gene/Protein Information For Rgs3 (Source: Uniprot.org, NCBI)

Alternative Names

Regulator of G-protein signaling 3;RGS3;C2PA;Rgs3; RGS3 C2PA, RGP3 regulator of G protein signaling 3 regulator of G-protein signaling 3|regulator of G-protein signalling 3

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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