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Product Info Summary
| SKU: | A14930 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Prosapip1 LZTS3 Antibody
SKU/Catalog Number
A14930
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Prosapip1 LZTS3 Antibody (Catalog # A14930). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Prosapip1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Prosapip1 LZTS3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A14930)
Host
Rabbit
Contents
Prosapip1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Prosapip1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human Prosapip1. The immunogen is located within amino acids 590 - 640 of Prosapip1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least two isoforms of NIPSNAP3A are known to exist. NIPSNAP3A antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
Reactive Species
A14930 is reactive to PROSAPIP1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
71791 MW
Background of ProSAPiP1
Prosapip1 is a binding partner of the postsynaptic density (PSD) protein ProSAP2/Shank3, a major scaffolding protein in excitatory brain synapses. Prosapip1 is thought to bind ProSAP2/Shank3 through ProSAP2/Shank3's PDZ domain and link it in turn to the Spine-associated Rap-Gap (SPAR). Prosapip1 shares significant homology with another PSD protein, PSD-Zip70, with both coding for a Fez1 domain that can be found in a total of four related protein, forming a novel family of scaffolding molecules termed ‘Fezzins'. Recent studies show that Prosapip1 can be found in endocrine cells in which it is localized primarily in the hormone-storing compartment of these cells, suggesting that Prosapip1 may have other functions in non-neuronal cells.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A14930 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Prosapip1 antibody can be used for detection of Prosapip1 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Prosapip1 in SK-N-SH cell lysate with Prosapip1 antibody at 1 μg/mL.
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Immunohistochemistry of Prosapip1 in rat brain tissue with Prosapip1 antibody at 2.5 μg/mL.
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Immunofluorescence of Prosapip 1 in rat brain tissue with Prosapip 1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PROSAPIP1 (Source: Uniprot.org, NCBI)
Gene Name
PROSAPIP1
Full Name
Leucine zipper putative tumor suppressor 3
Weight
71791 MW
Superfamily
LZTS3 family
Alternative Names
PROSAPIP1, KIAA0552, PROSAPIP1, Leucine zipper putative tumor suppressor 3, ProSAP-interacting protein 1, ProSAPiP1 LZTS3 PROSAPIP1 leucine zipper tumor suppressor family member 3 leucine zipper putative tumor suppressor 3|ProSAP/Shank-interacting protein 1|leucine zipper, putative tumor suppressor family member 3|proline rich synapse associated protein interacting protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PROSAPIP1, check out the PROSAPIP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PROSAPIP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Prosapip1 LZTS3 Antibody (A14930)
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