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Product Info Summary
| SKU: | PA1413 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Progesterone Receptor/PGR Antibody Picoband®
SKU/Catalog Number
PA1413
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Progesterone Receptor/PGR Antibody catalog # PA1413. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Progesterone Receptor/PGR Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1413)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Progesterone Receptor, identical to the related rat and mouse sesquences.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1413 is reactive to PGR in Human
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
36 kDa
Calculated molecular weight
98981 MW
Background of PGR
The progesterone receptor (PR) is an intracellular steroid receptor that specially binds progesterone in humans. PR has been a member of the steroid receptor superfamily. It is encoded by a single PGR gene residing on chromosome 11q22. The PGR gene uses separate promoters and translational start sites to produce 2 isoforms, PRA and PRB, which are identical except for an additional 165 amino acids present only in the N terminus of PRB. It can be observed in human breast tissues. The proteins function as dimeric molecules in nuclei to regulate the transcription of target genes in a ligand-responsive manner.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1413 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Positive Control
WB: HELA Cell
IHC: Human Rectal Cancer Tissue
Validation Images & Assay Conditions
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Anti-Progesterone Receptor antibody, PA1413, Western blotting
WB: HELA Cell Lysate
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Anti-Progesterone Receptor antibody, PA1413, IHC(P)
IHC(P): Human Rectal Cancer Tissue
Protein Target Info & Infographic
Gene/Protein Information For PGR (Source: Uniprot.org, NCBI)
Gene Name
PGR
Full Name
Progesterone receptor
Weight
98981 MW
Superfamily
nuclear hormone receptor family
Alternative Names
Progesterone receptor;PR;Nuclear receptor subfamily 3 group C member 3;PGR;NR3C3; PGR NR3C3, PR progesterone receptor progesterone receptor|nuclear receptor subfamily 3 group C member 3
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PGR, check out the PGR Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PGR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Progesterone Receptor/PGR Antibody Picoband® (PA1413)
Hello CJ!
PA1413 has been cited in 1 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Fu Y, Zhao Z, Wu Y, Wu K, Xu X, Liu Y, Tong C. J Ethnopharmacol. 2012 Jan 6;139(1):26-33. Doi: 10.1016/J.Jep.2011.08.077. Epub 2011 Nov 10. Therapeutic Mechanisms Of Tongmai Dasheng Tablet On Tripterygium Glycosides Induced Rat Model For Premature...
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-Progesterone Receptor/PGR Antibody Picoband®
Question
When shipping the product PA1413, will all the wet ice be thawed upon arrival of the package?
Verified customer
Asked: 2019-10-23
Answer
The wet ice would most likely be thawed upon arrival, but the Anti-Progesterone Receptor/PGR Antibody PA1413 is lyophilized, so it should be fine.
Boster Scientific Support
Answered: 2019-10-24
