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Product Info Summary
| SKU: | A13406 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Probable ribonuclease ZC3H12C ZC3H12C Antibody
SKU/Catalog Number
A13406
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Probable ribonuclease ZC3H12C ZC3H12C Antibody (Catalog # A13406). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ZC3H12C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Probable ribonuclease ZC3H12C ZC3H12C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A13406)
Host
Rabbit
Contents
ZC3H12C Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZC3H12C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12C. The immunogen is located within the first 50 amino acids of ZC3H12C.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of SLAIN1 are known to exist; this antibody will detect all three. SLAIN1 antibody is predicted not to cross-react with SLAIN2.
Reactive Species
A13406 is reactive to ZC3H12C in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
99340 MW
Background of ZC3H12C
ZC3H12C, also known as MCPIP3, is a member of a family of novel CCCH-zinc finger proteins that includes ZC3H12A, a protein that is thought to be involved in macrophage activation, host immunity and inflammatory diseases. Similar to ZC3H12A, ZC3H12C expression in macrophages is highly increased after treatment with lipopolysaccharide (LPS), suggesting it also may play a role in host immunity and inflammatory response.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A13406 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZC3H12C antibody can be used for detection of ZC3H12C by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZC3H12C in rat brain tissue lysate with ZC3H12C antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of ZC3H12C in human brain tissue with ZC3H12C antibody at 5 μg/mL.
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Immunofluorescence of ZC3H12C in human brain tissue with ZC3H12C antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ZC3H12C (Source: Uniprot.org, NCBI)
Gene Name
ZC3H12C
Full Name
Probable ribonuclease ZC3H12C
Weight
99340 MW
Superfamily
ZC3H12 family
Alternative Names
MCPIP3, KIAA1726, MCPIP3, Probable ribonuclease ZC3H12C, MCP-induced protein 3 ZC3H12C MCPIP3 zinc finger CCCH-type containing 12C probable ribonuclease ZC3H12C|MCP-induced protein 3|zinc finger CCCH domain-containing protein 12C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZC3H12C, check out the ZC3H12C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZC3H12C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Probable ribonuclease ZC3H12C ZC3H12C Antibody (A13406)
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