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Product Info Summary
| SKU: | A32244 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-PRKCDBP CAVIN3 Antibody
SKU/Catalog Number
A32244
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-PRKCDBP CAVIN3 Antibody (Catalog # A32244). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
PRKCDBP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-PRKCDBP CAVIN3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A32244)
Host
Rabbit
Contents
PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP. The immunogen is located within amino acids 150 - 200 of PRKCDBP.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
It is predicted to not cross-react with other members of the cavin family.
Reactive Species
A32244 is reactive to PRKCDBP in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
27701 MW
Background of CAVIN3
The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A32244 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 μg/ml.
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Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For PRKCDBP (Source: Uniprot.org, NCBI)
Gene Name
PRKCDBP
Full Name
Caveolae-associated protein 3
Weight
27701 MW
Superfamily
CAVIN family
Alternative Names
SRBC, HSRBC, CAVIN3, cavin-3, SRBC, Protein kinase C delta-binding protein, Cavin-3, hSRBC CAVIN3 HSRBC, PRKCDBP, SRBC, cavin-3 caveolae associated protein 3 caveolae-associated protein 3|protein kinase C delta binding protein|sdr-related gene product that binds to c-kinase|serum deprivation response factor-related gene product that binds to C-kinase
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PRKCDBP, check out the PRKCDBP Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PRKCDBP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PRKCDBP CAVIN3 Antibody (A32244)
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