PPP3CC Antibodies

AND PPP3CC ELISA kits, PPP3CC Proteins

Many biological assays use antibodies to detect PPP3CC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP3CC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP3CC antibodies...

We validate the specificity of these antibodies to PPP3CC by testing them on tissues known to express PPP3CC positively and negatively. Browse below to find the PPP3CC antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPP3CC Infographic by Boster Bio

All PPP3CC Products

Product

Figures

Specificity

Applications

Price

Anti-PPP3CC Antibody

Human, Mouse, Rat

$405
Cat # A07461
100ul

PPP3CC (NM_005605) Human Recombinant Protein

$1249
Cat # PROTP48454
20 µg

PPP3CC (NM_005605) Human Over-expression Lysate

Human

$628
Cat # LS005533
100 µg

Anti-PPP3CC Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A07461-1
100 µg/vial

PPP3CC Overview

Facts about Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform.

PPP3CC 3D structure. Source: alphafold

Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PPP3CC)

Calcium-dependent, calmodulin-stimulated protein phosphatase that plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Dephosphorylates and activates transcription factor NFATC1.

Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32.

Gene Information

Human
Gene Name:	PPP3CC
Uniprot:	P48454
Entrez:	5533

Family

Belongs to:

PPP phosphatase family

Alternative Names

Calcineurin, testis-specific catalytic subunit; Calmodulin-dependent calcineurin A subunit gamma isoform; CALNA3CAM-PRP catalytic subunit; CNA3; EC 3.1.3.16; PP2Bgamma; protein phosphatase 2B, catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform(calcineurin A gamma); protein phosphatase 3, catalytic subunit, gamma isozyme; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

Molecular Weight

Mass (kDA):
58.129 kDA

Genomic Context


Human

Location:	8p21.3
Sequence:	8; NC_000008.11 (22440970..22541466)

Tissue Specificity

Testis.

Diseases

Schizophrenia
Psychotic Disorders
Mental Disorders
Dysequilibrium Syndrome
Impairment (finding)
Malnutrition
Malignant Neoplasms
Neoplasms
Memory Impairment
Bipolar Disorder
Hereditary Diseases
Alzheimer's Disease
Schizoaffective Disorder

Mood Disorders
Neurodegenerative Disorders
Cardiac Hypertrophy
Parkinson Disease
Carcinoma
5,10-methylenetetrahydrofolate Reductase Deficiency
Cleft Lip

Interacting Proteins

AMPH
PPP3R1

Pathways

Pathogenesis
Protein Phosphorylation
Cell Death
Neuronal Signal Transduction
Social Behavior
Localization

PTMs

Phosphorylation

Dephosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP3CC

References

PMID: 1339277 by Muramatsu T., et al. Molecular cloning and chromosomal mapping of the human gene for the testis-specific catalytic subunit of calmodulin-dependent protein phosphatase (calcineurin A).

PMID: 19154138 by Kilka S., et al. The proline-rich N-terminal sequence of calcineurin Abeta determines substrate binding.