Anti-PPP1R16B/Timap Antibody

Product Name

Anti-PPP1R16B/Timap Antibody

View all PPP1R16B Antibodies

SKU/Catalog Number

A09221

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-PPP1R16B/Timap Antibody (Catalog # A09221). Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PPP1R16B/Timap Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09221)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human PPP1R16B.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A09221 is reactive to PPP1R16B in Human, Mouse

Reconstitution

Calculated molecular weight

63551 MW

Background of PPP1R16B

Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.

Cao W., Am. J. Physiol. 283:C327-C337(2002).
Nagase T., DNA Res. 5:355-364(1998).
Nakajima D., DNA Res. 9:99-106(2002).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A09221 is guaranteed for WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000

Validation Images & Assay Conditions

Gene/Protein Information For PPP1R16B (Source: Uniprot.org, NCBI)

Alternative Names

Protein phosphatase 1 regulatory inhibitor subunit 16B;Ankyrin repeat domain-containing protein 4;CAAX box protein TIMAP;TGF-beta-inhibited membrane-associated protein;hTIMAP;PPP1R16B;ANKRD4, KIAA0823; PPP1R16B ANKRD4, TIMAP protein phosphatase 1 regulatory subunit 16B protein phosphatase 1 regulatory inhibitor subunit 16B|CAAX box protein TIMAP|TGF-beta-inhibited membrane-associated protein|ankyrin repeat domain protein 4|ankyrin repeat domain-containing protein 4|hTIMAP|protein phosphatase 1, regulatory (inhibitor) subunit 16B

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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