Protein phosphatase 1 regulatory inhibitor subunit 16B (PPP1R16B)

Regulator of protein phosphatase 1 (PP1) which functions as a positive regulator of pulmonary endothelial cell (EC) barrier function (PubMed:18586956). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity (By similarity).

Protects the endothelial barrier from lipopolysaccharide (LPS)- induced vascular leakage (By similarity). Involved in the regulation of endothelial cell filopodia extension (By similarity).