Anti-Nucleoside phosphorylase/PNP Antibody Picoband®

Purine Nucleoside Phosphorylase/PNP antibody

Boster Bio Anti-Nucleoside phosphorylase/PNP Antibody Picoband® catalog # A00988-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: A00988-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: Flow Cytometry, IHC, WB

Product Name

Anti-Nucleoside phosphorylase/PNP Antibody Picoband®

View all Purine Nucleoside Phosphorylase/PNP Antibodies

SKU/Catalog Number

A00988-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Nucleoside phosphorylase/PNP Antibody Picoband® catalog # A00988-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Nucleoside phosphorylase/PNP Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00988-1)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A00988-1 is reactive to PNP in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

32 kDa

Calculated molecular weight

32118 MW

Background of Purine Nucleoside Phosphorylase/PNP

The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised Tlymphocyte function and neurologic dysfunction.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00988-1 is guaranteed for Flow Cytometry, IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Flow Cytometry (Fixed), 1-3μg/1x106 cells, Human

Positive Control

WB: human 293T whole cell, human PC-3 whole cell, rat liver tissue
IHC: mouse kidney tissue, rat kidney tissue, human liver cancer tissue, human renal cancer tissue
FCM: U937 cell, U251 cell

Validation Images & Assay Conditions

Gene/Protein Information For PNP (Source: Uniprot.org, NCBI)

Gene Name

PNP

Full Name

Purine nucleoside phosphorylase

Weight

32118 MW

Superfamily

PNP/MTAP phosphorylase family

Alternative Names

Purine nucleoside phosphorylase;PNP;2.4.2.1;Inosine phosphorylase;Inosine-guanosine phosphorylase;PNP;NP; PNP NP, PRO1837, PUNP purine nucleoside phosphorylase purine nucleoside phosphorylase|HEL-S-156an|epididymis secretory sperm binding protein Li 156an|inosine phosphorylase|inosine-guanosine phosphorylase|purine-nucleoside:orthophosphate ribosyltransferase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on PNP, check out the PNP Infographic

PNP infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for PNP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A00988-1

100μg

$370
A00988-1-10ug

10μg sample (liquid)

$99
A00988-1-Biotin

100 μg Biotin conjugated

$570
A00988-1-Cy3

100 μg Cy3 conjugated

$570
A00988-1-Dylight488

100 μg Dylight488 conjugated

$570
A00988-1-Dylight550

100 μg Dylight550 conjugated

$570
A00988-1-Dylight594

100 μg Dylight594 conjugated

$570
A00988-1-FITC

100 μg FITC conjugated

$570
A00988-1-HRP

100 μg HRP conjugated

$570
A00988-1-APC

100 μg APC conjugated

$670
A00988-1-PE

100 μg PE conjugated

$670
A00988-1-iFluor647

100 μg iFluor647 conjugated

$670
A00988-1-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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A00988-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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