Anti-PIN1 (phospho-S16) Antibody

Product Name

Anti-PIN1 (phospho-S16) Antibody

View all PIN1 Antibodies

SKU/Catalog Number

A00467S16

Size

100ul

Form

Liquid

Description

Boster Bio Anti-PIN1 (phospho-S16) Antibody catalog # A00467S16. Tested in WB,IHC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PIN1 (phospho-S16) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00467S16)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Pin1 around the non-phosphorylation site of S16.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A00467S16 is reactive to PIN1 in Human, Mouse, Rat

Applications

A00467S16 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

18243 MW

Background of PIN1

This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. Fibroblast Activation Protein (FAP)  is expressed in the stroma of sites that are undergoing wound healing. In addition, it has recently been reported that FAP is expressed in the stroma of sites of metastatic disease. Inhibition of FAP may lead to a dramatic decrease in the number of metastatic osteosarcoma lung nodules.  FAP exists as an inactive monomer and when activated forms homodimers or heterodimers with DPP4. Multiple isoforms of FAP are reported as alternative splicing products from a common gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200

Validation Images & Assay Conditions

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Western blot (WB) analysis of p-PIN1 (S16) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate treated with insulin(100nM,15min) Lane2:Raw264.7 cell lysate treated with insulin(100nM,15min) Lane3:PC12 cell lysate treated with insulin(100nM,15min)

Gene/Protein Information For PIN1 (Source: Uniprot.org, NCBI)

Alternative Names

dod; EC 5.2.1.8; peptidylprolyl cis/trans isomerase, NIMA-interacting 1; peptidyl-prolyl cis/trans isomerase, NIMA-interacting; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1; Rotamase Pin1; UBL5 PIN1 DOD, UBL5 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1|PPIase Pin1|protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1|protein interacting with never in mitosis A1|rotamase Pin1

For more info on PIN1, check out the PIN1 Infographic

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In this infographic, you will see the following information for PIN1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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