Anti-Phospho-Ron (Ser1394) Polyclonal Antibody

Product Name

Anti-Phospho-Ron (Ser1394) Polyclonal Antibody

View all MSPR/Ron Antibodies

SKU/Catalog Number

P01532

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Phospho-Ron (Ser1394) Polyclonal Antibody (Catalog # P01532). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-Ron (Ser1394) Polyclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P01532)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human Ron around the phosphorylation site of S1394.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

P01532 is reactive to MST1R in Human, Mouse

Applications

P01532 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

152271 MW

Background of MSPR/Ron

This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production.

Kristof Van Kolen, et al. (2006) FEBS J ; 273: 1843 - 1854.
Martin Villalba, et al. (2002) J. Cell Biol ; 157: 253.
Jie Zhang, et al. (2004) J. Biol. Chem ; 279: 22118 - 22123.
Castro AF, et al. (1998) Am J Physiol Cell Physiol; 275: C113 - C119.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1/500 - 1/2000
ELISA: 1/40000
Not yet tested in other applications.

Validation Images & Assay Conditions

Click image to see more details

Western Blot analysis of 3T3 cells using Phospho-Ron (S1394) Polyclonal antibody

Gene/Protein Information For MST1R (Source: Uniprot.org, NCBI)

Alternative Names

CD136 antigen; CD136; CDw136c-met-related tyrosine kinase; EC 2.7.10; EC 2.7.10.1; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); MSP R; MSP receptor; MSPR; MST1R; p185-Ron; Protein-tyrosine kinase 8; PTK8 protein tyrosine kinase 8; PTK8; Ron; RONmacrophage-stimulating protein receptor; soluble RON variant 1; soluble RON variant 2; soluble RON variant 3; soluble RON variant 4 MST1R CD136, CDw136, NPCA3, PTK8, RON, SEA macrophage stimulating 1 receptor macrophage-stimulating protein receptor|MSP receptor|PTK8 protein tyrosine kinase 8|S13 avian erythroblastosis oncogene homolog|S13 erythroblastosis oncogene homolog|c-met-related tyrosine kinase|p185-Ron

For more info on MST1R, check out the MST1R Infographic

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In this infographic, you will see the following information for MST1R: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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