Anti-Phospho-FADD (S194) Antibody

Product Name

Anti-Phospho-FADD (S194) Antibody

View all FADD Antibodies

SKU/Catalog Number

P00237

Size

100μl

Form

Liquid

Description

Boster Bio Anti-Phospho-FADD (S194) Antibody catalog # P00237. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Phospho-FADD (S194) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P00237)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human FADD around the phosphorylation site of S194 at AA range: 130-210 aa

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

P00237 is reactive to FADD in Human, Mouse

Applications

P00237 is guaranteed for ELISA, IHC-P, WB Boster Guarantee

Observed Molecular Weight

52 kDa

Calculated molecular weight

23279 MW

Background of FADD

Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alphasynuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders (Okochi et al., 2000). Mutation of the alpha-synuclein gene is associated with familial forms of PD (Newmann et al., 2002). Recent evidence suggests that phosphorylation of alpha-synuclein at Ser129 plays a role in the formation of inclusions in PD (Smith et al., 2005; Masliah et al., 2005).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of Mouse Kidney Mouse Brain Mouse Spleen Mouse Lung using p-FADD (S194) antibody.

Gene/Protein Information For FADD (Source: Uniprot.org, NCBI)

Alternative Names

FADD; Fas (TNFRSF6)-associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; GIG3; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; mediator of receptor-induced toxicity; MGC8528; MORT1; MORT1Fas-associating protein with death domain; protein FADD FADD GIG3, MORT1 Fas associated via death domain FAS-associated death domain protein|Fas (TNFRSF6)-associated via death domain|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor-induced toxicity

For more info on FADD, check out the FADD Infographic

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In this infographic, you will see the following information for FADD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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