Product Info Summary
SKU: | P02811 |
---|---|
Size: | 100 µl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Phospho-EphB1/2 (Tyr594/604) Antibody
SKU/Catalog Number
P02811
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Phospho-EphB1/2 (Tyr594/604) Antibody (Catalog # P02811). Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-EphB1/2 (Tyr594/604) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P02811)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human EphB1/2 around the phosphorylation site of Y594/604.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
P02811 is reactive to EPHB1 in Human, Mouse, Rat
Reconstitution
Calculated molecular weight
109885 MW
Background of EPHB1
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells.
Ferrer, et al. (2003) Neuropathology & Applied Neurobiology 29: 23
Zhonghong Guan, et al. (1999) J Biol Chem, Vol. 274: 36200-36206
D.Margriet Ouwens1, et al. (2002)The EMBO Journal 21: 3782
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
P02811 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blotting: 1/500 - 1/2000
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/5000
Not yet tested in other applications.
Validation Images & Assay Conditions
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Western Blot analysis of HELA A431 cells using Phospho-EphB1/2 (Y594/604) Polyclonal antibody
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Western Blot analysis of Hela cells using Phospho-EphB1/2 (Y594/604) Polyclonal antibody
Protein Target Info & Infographic
Gene/Protein Information For EPHB1 (Source: Uniprot.org, NCBI)
Gene Name
EPHB1
Full Name
Ephrin type-B receptor 1
Weight
109885 MW
Superfamily
protein kinase superfamily
Alternative Names
Ephrin type-B receptor 1;2.7.10.1;ELK;EPH tyrosine kinase 2;EPH-like kinase 6;EK6;hEK6;Neuronally-expressed EPH-related tyrosine kinase;NET;Tyrosine-protein kinase receptor EPH-2;EPHB1;ELK, EPHT2, HEK6, NET; EPHB1 ELK, EPHT2, Hek6, NET EPH receptor B1 ephrin type-B receptor 1|EK6|EPH-like kinase 6|eph tyrosine kinase 2|neuronally-expressed EPH-related tyrosine kinase|soluble EPHB1 variant 1|tyrosine-protein kinase receptor EPH-2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on EPHB1, check out the EPHB1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for EPHB1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-EphB1/2 (Tyr594/604) Antibody (P02811)
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No publications found for P02811
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