Product Info Summary
SKU: | A00556S637-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC, WB |
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Product info
Product Name
Anti-Phospho-DRP1 (S637) DNM1L Antibody
SKU/Catalog Number
A00556S637-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-DRP1 (S637) DNM1L Antibody catalog # A00556S637-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-DRP1 (S637) DNM1L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00556S637-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human DRP1 around the phosphorylation site of S637.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00556S637-1 is reactive to DNM1L in Human, Mouse, Rat
Applications
A00556S637-1 is guaranteed for ELISA, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
81877 MW
Background of DRP1
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Drane P., Oncogene 15:3013-3024(1997).
Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).
Naeaer A.M., Nature 398:828-832(1999).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Validation Images & Assay Conditions
![a00556s637 1 anti phospho drp1 s637 dnm1l antibody wb testing 1 a00556s637 1 anti phospho drp1 s637 dnm1l antibody wb testing 1](https://www.bosterbio.com/media/catalog/product/a/0/a00556s637-1-anti-phospho-drp1-s637-dnm1l-antibody-wb-testing-1.jpg)
Click image to see more details
Figure 1. Western blotting validation for Anti-Phospho-DRP1 (S637) DNM1L Antibody A00556S637-1
Western Blot (WB) analysis of JK cells using Phospho-DRP1 (S637) polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For DNM1L (Source: Uniprot.org, NCBI)
Gene Name
DNM1L
Full Name
Dynamin-1-like protein
Weight
81877 MW
Superfamily
TRAFAC class dynamin-like GTPase superfamily
Alternative Names
DLP1; DRP1Dnm1p/Vps1p-like protein; DVLPEC 3.6.5.5; Dymple; DYMPLEDYNIV-11; dynamin 1-like; Dynamin family member proline-rich carboxyl-terminal domain less; dynamin-1-like protein; Dynamin-like protein 4; Dynamin-like protein IV; Dynamin-like protein; Dynamin-related protein 1; FLJ41912; HDYNIV; VPS1 DNM1L DLP1, DRP1, DVLP, DYMPLE, EMPF, EMPF1, HDYNIV, OPA5 dynamin 1 like dynamin-1-like protein|Dnm1p/Vps1p-like protein|dynamin family member proline-rich carboxyl-terminal domain less|dynamin-like protein 4|dynamin-like protein IV|dynamin-related protein 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DNM1L, check out the DNM1L Infographic
![DNM1L infographic](/media/images/gene-infographic-example.jpg)
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DNM1L: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-DRP1 (S637) DNM1L Antibody (A00556S637-1)
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