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Product Info Summary
| SKU: | A00915 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-Pannexin-1 PANX1 Antibody
View all Pannexin-1 Antibodies
SKU/Catalog Number
A00915
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Pannexin-1 PANX1 Antibody (Catalog # A00915). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
PANX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Pannexin-1 PANX1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00915)
Host
Rabbit
Contents
PANX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1. The immunogen is located within amino acids 70 - 120 of PANX1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Two transcript variants encoding different isoforms have been found for this gene.
Reactive Species
A00915 is reactive to PANX1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
48050 MW
Background of Pannexin-1
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00915 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of PANX1 in human ovary tissue lysate with PANX1 antibody at 1 μg/mL.
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Immunofluorescence of PANX1 in human ovary tissue with PANX1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For PANX1 (Source: Uniprot.org, NCBI)
Gene Name
PANX1
Full Name
Pannexin-1
Weight
48050 MW
Superfamily
pannexin family
Alternative Names
PX1, MRS1, UNQ2529, UNQ2529/PRO6028, Pannexin-1 PANX1 MRS1, OOMD7, PX1, UNQ2529 pannexin 1 pannexin-1|innexin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PANX1, check out the PANX1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PANX1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Pannexin-1 PANX1 Antibody (A00915)
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