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Product Info Summary
| SKU: | A04211-1 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | IHC-P, WB |
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Product info
Product Name
Anti-PACSIN2 Antibody (C-term)
SKU/Catalog Number
A04211-1
Size
80 µl
Description
Boster Bio Anti-PACSIN2 Antibody (C-term) (Catalog # A04211-1). Tested in WB, IHC-P application(s). This antibody reacts with Human, Mouse.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-PACSIN2 Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04211-1)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human PACSIN2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04211-1 is reactive to PACSIN2 in Human, Mouse
Reconstitution
Calculated molecular weight
55739 Da
Background of PACSIN2
PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP). The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). The protein contains 1 FCH domain and 1 SH3 domain.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A04211-1 is guaranteed for IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
IHC-P: 1:50-1:100
Validation Images & Assay Conditions
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PACSIN2 Antibody (S357) western blot analysis in Daudi,HL-60 cell line and mouse brain,rat heart lysates (35ug/lane).This demonstrates the PACSIN2 antibody detected the PACSIN2 protein (arrow).
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Immunohistochemical analysis of paraffin-embedded H. stomach section using PACSIN2 Antibody (C-term). A04211-1 was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Protein Target Info & Infographic
Gene/Protein Information For PACSIN2 (Source: Uniprot.org, NCBI)
Gene Name
PACSIN2
Full Name
Protein kinase C and casein kinase substrate in neurons protein 2
Weight
55739 Da
Superfamily
PACSIN family
Alternative Names
Protein kinase C and casein kinase substrate in neurons protein 2, Syndapin-2, Syndapin-II, PACSIN2 PACSIN2 SDPII protein kinase C and casein kinase substrate in neurons 2 protein kinase C and casein kinase substrate in neurons protein 2|cytoplasmic phosphoprotein PACSIN2|syndapin-2|syndapin-II|syndapin2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on PACSIN2, check out the PACSIN2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for PACSIN2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-PACSIN2 Antibody (C-term) (A04211-1)
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