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Product Info Summary
| SKU: | A02456 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB, IF (paraffin) |
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Product info
Product Name
Anti-OAT1 SLC22A6 Antibody
SKU/Catalog Number
A02456
Size
100ul
Form
Liquid
Description
Boster Bio Anti-OAT1 SLC22A6 Antibody (Catalog# A02456). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-OAT1 SLC22A6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02456)
Host
Rabbit
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A peptide derived from human OAT1. Immunogen sequence location: 255 - 304
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A02456 is reactive to SLC22A6 in Human, Mouse, Rat
Applications
A02456 is guaranteed for ELISA, IHC-P, WB, IF (paraffin) Boster Guarantee
Observed Molecular Weight
72 kDa
Calculated molecular weight
61816 MW
Background of SLC22A6
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Assay dilution & Images
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western Blot, 1:500 - 1:2000
Immunohistochemistry, 1:100 - 1:300
ELISA, 1:20000
Not yet tested in other applications.
Validation Images & Assay Conditions
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Western blot analysis of lysate from mouse liver, using OAT1 antibody.
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Immunohistochemistry analysis of OAT1 antibody in paraffin-embedded human brain tissue.
Protein Target Info & Infographic
Gene/Protein Information For SLC22A6 (Source: Uniprot.org, NCBI)
Gene Name
SLC22A6
Full Name
Solute carrier family 22 member 6
Weight
61816 MW
Superfamily
major facilitator (TC 2.A.1) superfamily
Alternative Names
hOAT1; hPAHT; hROAT1; MGC45260; OAT1; OAT1FLJ55736; Organic anion transporter 1; PAH transporter; PAHT; PAHTHOAT1; para-aminohippurate transporter; Renal organic anion transporter 1; ROAT1; SLC22A6; solute carrier family 22 (organic anion transporter), member 6; solute carrier family 22 member 6 SLC22A6 HOAT1, OAT1, PAHT, ROAT1 solute carrier family 22 member 6 solute carrier family 22 member 6|PAH transporter|hPAHT|hROAT1|organic anion transporter 1|para-aminohippurate transporter|renal organic anion transporter 1|solute carrier family 22 (organic anion transporter), member 6
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC22A6, check out the SLC22A6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC22A6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-OAT1 SLC22A6 Antibody (A02456)
Hello CJ!
A02456 has been cited in 2 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
The Herbal Constituents in An-Gong-Niu-Huang Wan (AGNH) Protect against Cinnabar- and Realgar-Induced Hepatorenal Toxicity and Accumulations of Mercury and Arsenic in Mice
Songsong Wang,Xiao Xiao,Ao Li,Peng Li,"The Herbal Constituents in An-Gong-Niu-Huang Wan (AGNH) Protect against Cinnabar- and Realgar-Induced Hepatorenal Toxicity and Accumulations of Mercury and Arsenic in Mice",Evidence-Based Complementary and Alternative Medicine,vol.2021,Article ID 5566078,9 pages,2021.https://doi.org/10.1155/2021/5566078
Species: Mouse
A02456 usage in article: APP:WB, SAMPLE:HEPATORENAL TISSUE, DILUTION:NA
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