Anti-NTT4 SLC6A17 Antibody

Slc6a17 antibody

Boster Bio Anti-NTT4 SLC6A17 Antibody catalog # A12725. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A12725
Size: 100μl
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: WB

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Product Name

Anti-NTT4 SLC6A17 Antibody

View all Slc6a17 Antibodies

SKU/Catalog Number

A12725

Size

100μl

Form

Liquid

Description

Boster Bio Anti-NTT4 SLC6A17 Antibody catalog # A12725. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NTT4 SLC6A17 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12725)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human NTT4. at AA rangle: 240-320

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12725 is reactive to Slc6a17 in Human, Mouse, Rat

Applications

A12725 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

81001 MW

Background of Slc6a17

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

Gene/Protein Information For Slc6a17 (Source: Uniprot.org, NCBI)

Gene Name

Slc6a17

Full Name

Sodium-dependent neutral amino acid transporter SLC6A17

Weight

81001 MW

Superfamily

sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family

Alternative Names

NTT4; orphan sodium- and chloride-dependent neurotransmitter transporter NTT4; Sodium-dependent neurotransmitter transporter NTT4; solute carrier family 6 (neurotransmitter transporter), member 17; Solute carrier family 6 member 17; solute carrier family 6, member 17

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Slc6a17, check out the Slc6a17 Infographic

Slc6a17 infographic

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In this infographic, you will see the following information for Slc6a17: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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6 Customer Q&As for Anti-NTT4 SLC6A17 Antibody

Question

We are currently using anti-NTT4 antibody A12725 for rat tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on bovine tissues as well?

L. Edwards

Verified customer

Asked: 2020-02-25

Answer

The anti-NTT4 antibody (A12725) has not been tested for cross reactivity specifically with bovine tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in bovine you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-02-25

Question

Does anti-NTT4 antibody A12725 work on goat WB with hippocampus?

C. Brown

Verified customer

Asked: 2020-02-19

Answer

Our lab technicians have not tested anti-NTT4 antibody A12725 on goat. You can run a BLAST between goat and the immunogen sequence of anti-NTT4 antibody A12725 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated goat samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in goat hippocampus in WB, you can get your next antibody for free.

Boster Scientific Support

Answered: 2020-02-19

Question

Is a blocking peptide available for product anti-NTT4 antibody (A12725)?

Verified Customer

Verified customer

Asked: 2018-05-18

Answer

We do provide the blocking peptide for product anti-NTT4 antibody (A12725). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2018-05-18

Question

I am looking for to test anti-NTT4 antibody A12725 on rat hippocampus for research purposes, then I may be interested in using anti-NTT4 antibody A12725 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

Verified Customer

Verified customer

Asked: 2017-07-20

Answer

The products we sell, including anti-NTT4 antibody A12725, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2017-07-20

Question

Would A12725 anti-NTT4 antibody work on parafin embedded sections? If so, which fixation method do you recommend we use (PFA, paraformaldehyde, other)?

T. Singh

Verified customer

Asked: 2014-01-15

Answer

You can see on the product datasheet, A12725 anti-NTT4 antibody as been tested on WB. It is best to use PFA for fixation because it has better tissue penetration ability. PFA needs to be prepared fresh before use. Long term stored PFA turns into formalin, as the PFA molecules congregate and become formalin.

Boster Scientific Support

Answered: 2014-01-15

Question

Would anti-NTT4 antibody A12725 work for WB with hippocampus?

D. Johnson

Verified customer

Asked: 2013-03-07

Answer

According to the expression profile of hippocampus, SLC6A17 is highly expressed in hippocampus. So, it is likely that anti-NTT4 antibody A12725 will work for WB with hippocampus.

Boster Scientific Support

Answered: 2013-03-07

Order DetailsPrice
A12725

100uL

$399

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A12725
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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