Anti-NGFR Antibody

NGFR/TNFRSF16/p75NTR antibody

Boster Bio Anti-NGFR Antibody (Catalog # A01187-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Product Info Summary

SKU: A01187-1
Size: 0.1 mg
Reactive Species: Human, Mouse
Host: Rabbit
Application: ELISA, IF, ICC, WB

Product Name

Anti-NGFR Antibody

View all NGFR/TNFRSF16/p75NTR Antibodies

SKU/Catalog Number

A01187-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-NGFR Antibody (Catalog # A01187-1). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

NGFR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-NGFR Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01187-1)

Host

Rabbit

Contents

NGFR Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

NGFR antibody was raised against purified recombinant human NGFR.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

ZEB2 antibody is predicted to not cross-react with ZEB1.

Reactive Species

A01187-1 is reactive to NGFR in Human, Mouse

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

45183 MW

Background of NGFR/TNFRSF16/p75NTR

The tumor necrosis factor (TNF) and TNF receptor (TNFR) gene superfamilies regulate numerous biological functions including cell proliferation, differentiation, and survival through regulating the activation of the transcription factor NF-κB and various mitogen-activated protein kinases. Nerve growth factor receptor (NGFR) was one of the earliest characterized members of this family. Also known as the low-affinity receptor p75NTR, this receptor is involved in several diverse functions such as apoptosis, neurite outgrowth during development, and myelination. Its ligands include NGF, brain-derived neurotrophic factor (BDNF), NT3, and NT4. NGFR can also associate with other NGF receptors such as Trk through the cytosolic and transmembrane domains and thus can function as a co-receptor that refines Trk affinity and specificity for neurotrophins. Finally, upon binding of various neurotrophins, NGFR associates with tumor necrosis factor receptor-6 (TRAF6), suggesting that it can potentially function as a signal transducer for NGF signals through NGFR.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01187-1 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

NGFR antibody can be used for the detection of NGFR by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 10 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in human samples. . All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For NGFR (Source: Uniprot.org, NCBI)

Gene Name

NGFR

Full Name

Tumor necrosis factor receptor superfamily member 16

Weight

45183 MW

Alternative Names

CD271, p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, Tumor necrosis factor receptor superfamily member 16, NGF receptor NGFR CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR nerve growth factor receptor tumor necrosis factor receptor superfamily member 16|NGF receptor|TNFR superfamily, member 16|low affinity neurotrophin receptor p75NTR|low-affinity nerve growth factor receptor|p75 ICD

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on NGFR, check out the NGFR Infographic

NGFR infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for NGFR: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01187-1-0.1 mg

0.1 mg

$449

Free Secondary Antibody

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A01187-1
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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$449.00

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