Anti-Neuropilin-2 NRP2 Antibody

Product Name

Anti-Neuropilin-2 NRP2 Antibody

View all Neuropilin-2 Antibodies

SKU/Catalog Number

A02820

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Neuropilin-2 NRP2 Antibody catalog # A02820. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Neuropilin-2 NRP2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02820)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2 at amino acid range 791-840

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A02820 is reactive to NRP2 in Human, Mouse, Rat

Applications

A02820 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

104831 MW

Background of Neuropilin-2

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth.

Jiang-Hong Man, Nucleic Acids Res., Nov 2006; 34: 5552 - 5566.
Amir Sonnenblick, Mol. Cell. Biol., Dec 2004; 24: 10584 - 10592.
Jianyin Long, PNAS, Jan 2004; 101: 99.
Hyun Duk Jang, J. Biol. Chem., Jun 2004; 279: 24873 - 24880.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000

Validation Images & Assay Conditions

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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100

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Western blot analysis of HepG2 cells using Neuropilin-2 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000.

Gene/Protein Information For NRP2 (Source: Uniprot.org, NCBI)

Alternative Names

MGC126574; neuropilin 2; Neuropilin2; Neuropilin-2; neuropilin-2a(22); neuropilin-2b(0); NP2; NPN 2; NPN2; PRO2714; receptor for VEGF165 and semaphorins class3; Vascular endothelial cell growth factor 165 receptor 2; vascular endothelial growth factor-165 receptor 2; VEGF1265R2; VEGF165R2neuropilin-2a(17) NRP2 NP2, NPN2, PRO2714, VEGF165R2 neuropilin 2 neuropilin-2|neuropilin-2a(17)|neuropilin-2a(22)|neuropilin-2b(0)|receptor for VEGF165 and semaphorins class3|vascular endothelial cell growth factor 165 receptor 2

For more info on NRP2, check out the NRP2 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for NRP2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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