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Product Info Summary
| SKU: | A03636 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-NALP6 NLRP6 Antibody
SKU/Catalog Number
A03636
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NALP6 NLRP6 Antibody (Catalog # A03636). Tested in ELISA, WB, IF applications. This antibody reacts with Human.
Storage & Handling
NALP6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-NALP6 NLRP6 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03636)
Host
Rabbit
Contents
NALP6 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
NALP6 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP6. The immunogen is located within amino acids 150 - 200 of NALP6.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
At least three isoforms of KIF5 are known to exist; this antibody will recognize all three isoforms.
Reactive Species
A03636 is reactive to NLRP6 in Human
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
98768 MW
Background of NALP6
NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-κB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03636 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
NALP6 antibody can be used for detection of NALP6 by Western blot at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Immunofluorescence of NALP6 in human brain tissue with NALP6 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For NLRP6 (Source: Uniprot.org, NCBI)
Gene Name
NLRP6
Full Name
NACHT, LRR and PYD domains-containing protein 6
Weight
98768 MW
Superfamily
NLRP family
Alternative Names
AVR, NAVR, PAN3, NALP6, PYPAF5, CLR11.4, NAVR/AVR, NACHT, LRR and PYD domains-containing protein 6, PYRIN-containing APAF1-like protein 5 Nlrp6|AI504961, Avr, N, Nalp6, Navr, Navr/Avr, Non-AVR, Pypaf5|NLR family, pyrin domain containing 6|NACHT, LRR and PYD domains-containing protein 6|NACHT, leucine rich repeat and PYD containing 6|NACHT/LRR/pyrin domain-containing protein 6|PYRIN-containing APAF1-like protein 5|angiotensin II/vasopressin receptor|non-angiotensin-vasopressin receptor
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NLRP6, check out the NLRP6 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NLRP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NALP6 NLRP6 Antibody (A03636)
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No publications found for A03636
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