Anti-MYT1L Antibody

Product Name

Anti-MYT1L Antibody

View all Myt1l Antibodies

SKU/Catalog Number

A07880

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-MYT1L Antibody (Catalog # A07880). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

MYT1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-MYT1L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A07880)

Host

Rabbit

Contents

MYT1L Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

Rabbit polyclonal MYT1L antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MYT1L. The immunogen is located within the last 50 amino acids of MYT1L.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least three isoforms are known to exist. This antibody will only recognize the two longest isoforms.

Reactive Species

A07880 is reactive to Myt1l in Human, Mouse, Rat

Applications

A07880 is guaranteed for ELISA, IF, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

133043 MW

Background of Myt1l

The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

MYT1L antibody can be used for detection of MYT1L by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of MYT1L in mouse brain tissue lysate with MYT1L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

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Immunofluorescence of MYT1L in human brain with MYT1L antibody at 20 μg/mL.

Gene/Protein Information For Myt1l (Source: Uniprot.org, NCBI)

Alternative Names

KIAA1106neural zinc finger transcription factor 1; myelin transcription factor 1-like protein; myelin transcription factor 1-like; MyT1L; MyT1-L; NZF1 Myt1l|2900046C06Rik, 2900093J19Rik, C630034G21Rik, Nztf, Nztf1, Pmn, Pmng1, Png, Png-1, mKIAA1106|myelin transcription factor 1-like|myelin transcription factor 1-like protein|NZF-1|myT1-L|neural zinc finger factor 1|neural zinc finger protein NZF-1|neural zinc finger transcription factor 1|postmeiotic neural gene 1|postmitotic neural gene 1 protein|zinc finger protein Png-1

For more info on Myt1l, check out the Myt1l Infographic

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In this infographic, you will see the following information for Myt1l: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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