Myt1l Antibodies

AND Myt1l ELISA kits, Myt1l Proteins

Many biological assays use antibodies to detect Myt1l, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myt1l in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myt1l antibodies...

We validate the specificity of these antibodies to Myt1l by testing them on tissues known to express Myt1l positively and negatively. Browse below to find the Myt1l antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Myt1l Infographic by Boster Bio

All Myt1l Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MYT1L Antibody

Human, Mouse, Rat

ELISA, IF, WB

$449
Cat # A07880
0.1 mg

MYT1L (NM_015025) Human Over-expression Lysate

Human

$960
Cat # LS023040
100 µg

Anti-MYT1L Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A07880-1
100 µg/vial

Myt1l Overview

Facts about Myelin transcription factor 1-like protein.

Myelin transcription factor 1-like protein (Myt1l)

Transcription factor that plays a key role in neuronal differentiation by especially repressing expression of non- neuronal genes during neuron differentiation (PubMed:28379941). Compared to other transcription repressors that inhibit particular lineages, mediates repression of multiple differentiation programs (PubMed:28379941).

Also represses expression of negative regulators of neurogenesis, like members of the Notch signaling pathway, such as HES1 (PubMed:28379941). The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is enough to reprogram fibroblasts and other somatic cells to induced neuronal (iN) cells in vitro (PubMed:20107439, PubMed:24243019, PubMed:27281220).

Gene Information

Mouse
Gene Name:	Myt1l
Uniprot:	P97500
Entrez:	17933

Family

Belongs to:

MYT1 family

Alternative Names

KIAA1106neural zinc finger transcription factor 1; myelin transcription factor 1-like protein; myelin transcription factor 1-like; MyT1L; MyT1-L; NZF1

Molecular Weight

Mass (kDA):
132.945 kDA

Genomic Context


Mouse

Location:	12 A2\|12 11.86 cM
Sequence:	12;

Tissue Specificity

Brain.

Diseases

Schizophrenia
Depressive Disorder
Nervousness
Chromosomal Duplication
Mental Disorders
Major Depressive Disorder
Malnutrition
Neurodegenerative Disorders
Glioma
Neoplasms
Cytogenetic Abnormality

Neurobehavioral Manifestations
Embryonic Mosaic
Postmortem Changes
Glioblastoma
Nervous System Disorder

Pathways

Neurogenesis
Localization
Regeneration
Axon Extension
Insulin Secretion
Mitosis
Cell Differentiation
Brain Development
Axon Regeneration

Neuron Development
Oligodendrocyte Differentiation
Secretion

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Myt1l

References

PMID: 9130664 by Weiner J.A., et al. Png-1, a nervous system-specific zinc finger gene, identifies regions containing postmitotic neurons during mammalian embryonic development.

PMID: 9373037 by Kim J.G., et al. Myelin transcription factor 1 (Myt1) of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system.