Anti-Myc target protein 1 MYCT1 Antibody

Product Name

Anti-Myc target protein 1 MYCT1 Antibody

View all Myct1 Antibodies

SKU/Catalog Number

A12155

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Myc target protein 1 MYCT1 Antibody (Catalog # A12155). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-Myc target protein 1 MYCT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12155)

Host

Rabbit

Contents

MYCT1 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

At least two isoforms of MYCT1 are known to exist; this antibody will detect both isoforms.

Reactive Species

A12155 is reactive to Myct1 in Human, Mouse, Rat

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

26593 MW

Background of Myct1

MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A12155 is guaranteed for ELISA, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Positive Control

Validation Images & Assay Conditions

Click image to see more details

Western blot analysis of MYCT1 in rat lung tissue lysate with MYCT1 antibody at (A) 1 and (B) 2 μg/mL.

Gene/Protein Information For Myct1 (Source: Uniprot.org, NCBI)

Alternative Names

Myc target protein 1

For more info on Myct1, check out the Myct1 Infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Myct1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Take me to the Myct1 Infographic

Here are featured tools and databases that you might find useful.

• Boster's Pathways Library
• Protein Databases
• Bioscience Research Protocol Resources
• Data Processing & Analysis Software
• Photo Editing Software
• Scientific Literature Resources
• Research Paper Management Tools
• Molecular Biology Software
• Primer Design Tools
• Bioinformatics Tools
• Phylogenetic Tree Analysis