Product Info Summary
SKU: | P02351 |
---|---|
Size: | 100 µl |
Reactive Species: | Mouse, Rat |
Host: | Rabbit |
Application: | IHC, WB |
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Product info
Product Name
Anti-Phospho-Munc18-1 (Ser241) STXBP1 Antibody
View all Syntaxin-BP1 Antibodies
SKU/Catalog Number
P02351
Size
100 µl
Form
Liquid
Description
Boster Bio Anti-Phospho-Munc18-1 (Ser241) STXBP1 Antibody (Catalog # P02351). Tested in WB, IHC applications. This antibody reacts with Mouse, Rat.
Storage & Handling
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C. After date of receipt, stable for at least 1 year at -20°C.
Cite This Product
Anti-Phospho-Munc18-1 (Ser241) STXBP1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # P02351)
Host
Rabbit
Contents
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser241 of mouse Munc18-1, conjugated to keyhole limpet hemocyanin (KLH). Immunogen species is Mouse.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
P02351 is reactive to STXBP1 in Mouse, Rat
Reconstitution
Observed Molecular Weight
52 kDa
Calculated molecular weight
67569 MW
Background of Syntaxin-BP1
Munc-18 (mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc18-1 is thought to be regulated by phosphorylation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
P02351 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1000
IHC: 1:500
Validation Images & Assay Conditions
Click image to see more details
Western blot of mouse hippocampal lysate showing specific immunolabeling of the ~65 kDa Munc18-1 protein phosphorylated at Ser241 in the first lane (-). Phosphospecificity is shown in the second lane (+) where immunolabeling is completely eliminated by blot treatment with lambda phosphatase (gamma-Ptase, 1200 units for 30 min).
Protein Target Info & Infographic
Gene/Protein Information For STXBP1 (Source: Uniprot.org, NCBI)
Gene Name
STXBP1
Full Name
Syntaxin-binding protein 1
Weight
67569 MW
Superfamily
STXBP/unc-18/SEC1 family
Alternative Names
FLJ37475 antibody, Munc 18 1 antibody, Munc 18a antibody, MUNC18 1 antibody, N-Sec1 antibody, Neuronal SEC1 antibody, NSec1 antibody, p67 antibody, Protein unc-18 homolog 1 antibody, Protein unc-18 homolog A antibody, Rb sec1 antibody, RBSEC1 antibody, STXB1_HUMAN antibody, STXBP1 antibody, Syntaxin binding protein 1 antibody, Syntaxin-binding protein 1 antibody, Unc 18 homolog antibody, Unc 18A antibody, Unc-18A antibody, Unc18 1 antibody, UNC18 antibody, Unc18-1 antibody STXBP1 DEE4, MUNC18-1, N-Sec1, NSEC1, P67, RBSEC1, UNC18, unc-18A, unc18-1 syntaxin binding protein 1 syntaxin-binding protein 1|neuronal SEC1|protein unc-18 homolog 1|protein unc-18 homolog A
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on STXBP1, check out the STXBP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for STXBP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-Munc18-1 (Ser241) STXBP1 Antibody (P02351)
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No publications found for P02351
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Customer Reviews
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Customer Q&As
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3 Customer Q&As for Anti-Phospho-Munc18-1 (Ser241) STXBP1 Antibody
Question
Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for skin using anti-Phospho-Munc18-1 (Ser241) antibody P02351. Let me know if you need anything else.
Verified Customer
Verified customer
Asked: 2020-04-23
Answer
Thank you for the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.
Boster Scientific Support
Answered: 2020-04-23
Question
Do you have a BSA free version of anti-Phospho-Munc18-1 (Ser241) antibody P02351 available?
Verified Customer
Verified customer
Asked: 2019-12-23
Answer
We appreciate your recent telephone inquiry. I can confirm that some lots of this anti-Phospho-Munc18-1 (Ser241) antibody P02351 are BSA free. For now, these lots are available and we can make a BSA free formula for you free of charge. It will take 3 extra days to prepare. If you require this antibody BSA free again in future, please do not hesitate to contact me and I will be pleased to check which lots we have in stock that are BSA free.
Boster Scientific Support
Answered: 2019-12-23
Question
I see that the anti-Phospho-Munc18-1 (Ser241) antibody P02351 works with WB, what is the protocol used to produce the result images on the product page?
S. Moore
Verified customer
Asked: 2019-02-05
Answer
You can find protocols for WB on the "support/technical resources" section of our navigation menu. If you have any further questions, please send an email to [email protected]
Boster Scientific Support
Answered: 2019-02-05