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Product Info Summary
| SKU: | A05288 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-MTCH2 Antibody
SKU/Catalog Number
A05288
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-MTCH2 Antibody (Catalog # A05288). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.
Storage & Handling
MTCH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-MTCH2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05288)
Host
Rabbit
Contents
MTCH2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
MTCH2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist; this antibody will detect all but isoform b.
Reactive Species
A05288 is reactive to MTCH2 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
33499 MW
Background of MTCH2
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A05288 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 μg/mL.
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Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 μg/mL.
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Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For MTCH2 (Source: Uniprot.org, NCBI)
Gene Name
MTCH2
Full Name
Mitochondrial carrier homolog 2
Weight
33499 MW
Superfamily
mitochondrial carrier (TC 2.A.29) family
Alternative Names
HSPC032, 2310034D24Rik, 4930539J07Rik, Mitochondrial carrier homolog 2 MTCH2 HSPC032, MIMP, SLC25A50 mitochondrial carrier 2 mitochondrial carrier homolog 2|2310034D24Rik|met-induced mitochondrial protein|solute carrier family 25, member 50
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MTCH2, check out the MTCH2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MTCH2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MTCH2 Antibody (A05288)
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