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Product Info Summary
| SKU: | M01286 |
|---|---|
| Size: | 80 µl |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Mouse Kdm6a Antibody (C-term)
SKU/Catalog Number
M01286
Size
80 µl
Description
Boster Bio Anti-Mouse Kdm6a Antibody (C-term) (Catalog # M01286). Tested in WB application(s). This antibody reacts with Mouse.
Storage & Handling
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Cite This Product
Anti-Mouse Kdm6a Antibody (C-term) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01286)
Host
Rabbit
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
This mouse Kdm6a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1041-1074 amino acids from the C-terminal region of mouse Kdm6a.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01286 is reactive to Kdm6a in Mouse
Reconstitution
Calculated molecular weight
154355 Da
Background of KDM6A
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (By similarity).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M01286 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:2000
Validation Images & Assay Conditions
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All lanes : Anti-Kdm6a Antibody (C-term) at 1:2000 dilution
Lane 1: mouse cerebellum lysates
Lane 2: mouse spleen lysates
Lysates/proteins at 20 µg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size : 154 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
Protein Target Info & Infographic
Gene/Protein Information For Kdm6a (Source: Uniprot.org, NCBI)
Gene Name
Kdm6a
Full Name
Lysine-specific demethylase 6A
Weight
154355 Da
Superfamily
UTX family
Alternative Names
Lysine-specific demethylase 6A, 11411-, Histone demethylase UTX, Ubiquitously transcribed TPR protein on the X chromosome, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein, Kdm6a, Utx KDM6A KABUK2, UTX, bA386N14.2 lysine demethylase 6A lysine-specific demethylase 6A|[histone H3]-trimethyl-L-lysine(27) demethylase 6A|bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX))|histone demethylase UTX|lysine (K)-specific demethylase 6A|ubiquitously transcribed tetratricopeptide repeat protein X-linked|ubiquitously-transcribed TPR gene on the X chromosome
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Kdm6a, check out the Kdm6a Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Kdm6a: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Mouse Kdm6a Antibody (C-term) (M01286)
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